Effects of Perioperative Hyperoxygenation on Surgical Site Infection in Patients with Acute Appendicitis
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 7
Abstract
Introduction: Surgical wound infection is nightmare for any surgeon following elective and emergency operations. In recent studies, the possibility of reducing surgical site infection (SSI) by perioperative hyperoxygenation has been raised. Hypoxia at the level of local wound site retards proper healing. Proper oxygenation of the tissue through microcirculation is vital for the healing process and resistance to infection. The data obtained from the related randomized, controlled trials for the benefits of perioperative hyperoxygenation to reduce SSI remain controversial. To overcome this problem, we have performed a randomized, controlled trial in a patient population with a single diagnosis (acute appendicitis), using standard surgical approach (open appendicectomy).
Authors and Affiliations
P Harsh, K Hemanth, R Surekha
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