Efficacy of Azithromycin Injection Combined with Levofloxacin Capsule and Ambroxol Injection in the Treatment of Mycoplasma Pneumonia
Journal Title: Journal of Experimental and Clinical Application of Chinese Medicine - Year 2024, Vol 5, Issue 2
Abstract
Objective: To investigate the clinical efficacy and safety of combining azithromycin injection with levofloxacin capsule and ambroxol injection for the treatment of Mycoplasma pneumonia. Methods: A total of 160 cases of patients with mycoplasma pneumonia were randomly assigned to either the control group or the experimental group, with 80 cases in each group. In the control group, azithromycin injection was administered at a dosage of 10 mg/kg once daily via intravenous drip. The experimental group received treatment based on the control group regimen, supplemented with levofloxacin capsules at a dosage of 0.2 g (2 capsules) twice daily and ambroxol injection at a dosage of 1.2-1.6 mg/(kg.d), given 2-3 times per day through slow intravenous injection lasting for 2-3 minutes. Both groups underwent a treatment duration of 7 days. Clinical efficacy, antipyretic time, cough extinction time, lung rales extinction time, and adverse drug reactions were compared between the two groups. Results: The test group exhibited an effective treatment rate of 88% for mycoplasma pneumonia, whereas the control group was 74%. The test group demonstrated significantly shorter durations for fever, cough, and lung rale disappearance compared to the control group. Conclusion: The combination of azithromycin, levofloxacin, and ambroxol significantly enhances the efficacy in treating mycoplasma pneumonia. It can further shorten improvement signs and has high safety. It is worth application for non-pediatric patients with mycoplasma infection.
Authors and Affiliations
Ruizhen Meng, Zuomin Wu, Qi Song, Rui Wang
Keywords
Related Articles
- EP ID EP746604
- DOI https://doi.org/10.62767/jecacm502.3080
- Views 2
- Downloads 0
Exploring the Mechanism of Astragalus membranaceus in the Treatment of Post-Infectious Irritable Bowel Syndrome Based on Random Walk with Restart Algorithm and Experimental Validation
Background: This study aims to screen target genes with high relevance by running the random walk with restart (RWR) algorithm on the target background network, and to explore the mechanism of Astragalus membranaceus (AM...
Dynamic Changes of Phytohormone Concentrations during Prunella vulgaris L. Development and Impact of Rosmarinic Acid Accumulation through Exogenous ABA Application
Background: Plant hormones not only participate in regulating the growth and development process of plants, but also play an important regulatory role in the synthesis of secondary metabolites. Prunella vulgaris L. (P. v...
Rhizoma Zedoariae Inhibits G-CSF-Induced MDSCs-like Differentiation of THP-1 Cells
Objective: Rhizoma Zedoariae is widely used in the treatment of solid tumors in China, but there has been no deep research on its role in the formation of timmunosuppressive environments mediated by myeloid-derived suppr...
Exploring the Potential of Lotus Leaf and Its Bioactive Compounds for Anti-obesity Interventions
The complex syndrome of obesity is a complex syndrome associated with various metabolic disorders, poses significant threats to human health. Many weight loss medications have the potential to rapidly treat obesity, howe...
Effect of Jinhuahecha—A Fermented Green Tea on DSS-Induced Ulcerative Colitis in Mice and Its Preliminary Pharmacological Mechanism
Background: Ulcerative colitis (UC) is an inflammatory bowel disease. Jinhuahecha (JHHC)-a fermented green tea is obtained by micro-fermentation of Anji white tea (AJWT) inoculated with high-purity "E. cristatum". Purpos...