Pharmacological Effects of Polygonati Rhizoma on "Tonifying the Kidney" and Its Development Status in the Field of Health Care
Journal Title: Journal of Experimental and Clinical Application of Chinese Medicine - Year 2024, Vol 5, Issue 2
Abstract
Polygonati Rhizoma has traditional effects of tonifying the kidney, with a wide clinical application. The record of Polygonati Rhizoma can be traced back to Miscellaneous Records of Famous Physicians, where Polygonati Rhizoma was catalogued "to mainly tonify and replenish qi, and long-time administration can make the body agile, prolong life and relieve hunger". In modern times, Pharmacopoeia of the People’s Republic of China 2020 also records its effect of tonifying the kidney. In this study, the records of the related functions of Polygonati Rhizoma mainly in three aspects, "prolonging life", "tonifying essence and marrow", and "strengthening muscles and bones", were first sorted out in ancient and modern classics. This study also collected relevant prescriptions, such as Polygonati Rhizoma pill, and Polygonati Rhizoma and Radix Rehmanniae pill, with kidney-tonifying effects from 8 medical books including Arcane Essentials from the Imperial Library, Formulas from Benevolent Sages Compiled during the Taiping Era, Comprehensive Recording of Divine Assistance, etc. Through further retrieval of literature and analyses, it was confirmed that the pharmacological effects of Polygonati Rhizoma on "tonifying the kidney" contain improvement of arthritis and osteoporosis, anti-aging, immunoregulation, anti-fatigue, improvement of renal injury, improvement of reproductive function and anti-hypertension. The search and statistical analyses of special food information in State Administration for Market Regulation revealed that there are 409 kinds of health-care foods, with Polygonati Rhizoma as the main raw material, which have 15 kinds of health-care functions. Among them, "kidney-tonifying" health-care products that can enhance immunity, resist fatigue, elevate bone density or delay aging accounts over 80%. The last part of this study discussed and analyzed the pharmacological research progression of Polygonati Rhizoma on "tonifying the kidney" and its development status in the field of health care, so as to provide reference for in-depth development and application of Polygonati Rhizoma.
Authors and Affiliations
Wenlong Zhang, Kejian Wei, Su Gao, Zimo Dong, Jie Su
Rhizoma Zedoariae Inhibits G-CSF-Induced MDSCs-like Differentiation of THP-1 Cells
Objective: Rhizoma Zedoariae is widely used in the treatment of solid tumors in China, but there has been no deep research on its role in the formation of timmunosuppressive environments mediated by myeloid-derived suppr...
Automated, Microscopic Measurement of Fibrinaloid Microclots and Their Degradation by Nattokinase, the Main Natto Protease
Nattokinase, from the Japanese fermented food natto, is a protease with fibrinolytic activity that can thus degrade conventional blood clots. In some cases, however, including in Long COVID, fibrinogen can polymerise int...
Traditional Chinese Medicine in Colorectal Cancer Therapy: A Focus on Panax quinquefolium L. through Text Mining and Network Medicine Approaches
Background: This study aimed to identify traditional Chinese medicines (TCMs) with potential anti-colorectal cancer (CRC) properties and their core active constituents. Methods: A comprehensive review of the literature r...
Exploring the Potential of Lotus Leaf and Its Bioactive Compounds for Anti-obesity Interventions
The complex syndrome of obesity is a complex syndrome associated with various metabolic disorders, poses significant threats to human health. Many weight loss medications have the potential to rapidly treat obesity, howe...
Application of Tongbian Scraping Combined with Suhuang Zhike Capsule in Chronic Obstructive Pulmonary Disease
Objective: This study investigates the application of Tongbian scraping combined with Suhuang Zhike capsule in chronic obstructive pulmonary disease (COPD). Methods: 43 patients with COPD treated with Tongbian scraping c...