Efficacy of CPAP in Treatment of Hyaline Membrane Disease in NICU
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Hyaline membrane disease also called as respiratory is a common cause of admission in the NICU. It is a common health problem in preterm babies due to deficiency of surfactant. Surfactant reduces surface tension in the alveoli, prevents atelectasis and maintains stability continuous positive airway pressure (CPAP) that provides continuous distending pressure to the alveoli overcomes collapse and improves ventilation. Objective: To study the efficacy of CPAP in the management of respiratory distress syndrome in NICU Study Design: prospective hospital based longitudinal study. Subject: All newborn, admitted to the NICU with signs of respiratory distress with onset within first 6hrs of life and chest x-ray suggestive of RDS were included. Intervention: Bubble CPAP. Results: Thirty-two babies out of forty-two were successfully weaned off CPAP with overall CPAP success rate of 80.2 %. There were significant differences in mean oxygen saturations pre-CPAP (78±4.07) and post-CPAP (96.00±1.11) commencement (p= 0.001). The mean birth weight of survivors were higher (1235.2) compared to those who died (923.04 gms), with a p-value of <0.05. Babies that died had lower mean gestational age 28.3 weeks) than thosethat did not (32.3 weeks) though this was not statistically significant (p >0.05). Conclusion Noninvasive modalities of treatment like CPAP is cornerstone in treatment of mild to moderate cases of RDS. Its affordability, feasibility and good safety profile makes it treatment of choice in low income set up...
Authors and Affiliations
Rohini Panigrahi, Rabindra Nath Panda
Keywords
Related Articles
- EP ID EP539123
- DOI 10.21276/ijmrp.2018.4.2.044
- Views 74
- Downloads 0
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