Efficacy of Dexmedetomidine as an adjutant to Levobupivacaine for Supraclavicular Brachial Plexus Block
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Background and Aims: This prospective, randomised double blind study was conducted to establish the effects of addition of dexmedetomidine to levobupivacaine for supraclavicular brachial plexus block. Methods and Material: Sixty patients of ASA I&II, scheduled for upper arm surgery under supraclavicular block were enrolled to receive either 30 ml levobupivacaine 0.5% and 1 ml sodium chloride (Group I) OR 30 ml levobupivacaine 0.5% and 1 ml dexmedetomidine 100 microgram (Group II). Block was performed using nerve locator. The onset of sensory and motor block, duration of block and analgesia, VAS score and time of first rescue analgesia, haemodynamic variables and any side effects were monitored. Results: Demographic data was comparable between the groups. Sensory block onset time was 10.54±2.333 min in group I and 3.24±0.951 min in group II; motor block onset time was 12.21±2.529 min in group I and 3.83±1.197 min in group II; sensory block duration was 7.79±2.007 hours and 16.31±2.606 hours in group I and II respectively; motor block duration was 9.18±1.701 hour in group I and 17.52±2.098 hour in group II; time of first analgesic requirement was longer in group II than in group I (p<0.05). Intraoperative HR and BP were significantly lower in group II as compared to group I (p<0.05). Bradycardia was observed in one patient in group II with no other adverse effects in either of the groups. Conclusions: Hence, addition of dexmedetomidine to levobupivacaine for supraclavicular block significantly prolonged the duration of postoperative analgesia with added advantage of conscious sedation, haemodynamic stability with minimal side effects.
Authors and Affiliations
Dr. Mallika Mohindra, Dr. Anupama Gupta
Keywords
Related Articles
- EP ID EP256072
- DOI 10.9790/0853-1609057175
- Views 124
- Downloads 0
Quantitative Analysis of Apical Extrusion of Debris by Different Retreatment File Systems
Aim: To assess the effect of various retreatment file systems on apical debris extrusion. Material & method: Extracted human maxillary premolars were biomechanically prepared and obturated with gutta percha. They were di...
Opinions of Final Year and Interns about the EducationalEnviroment and Medical Curriculum At Jazan University
Aim of this study: This study was aimed to assess the opinions of 6th years and interns subjects about the learning and program experience at College of Medicine, Jazan University (CMJU) . Subjects and methods:A total nu...
CD4+T- Lymphocytes And Alanine Aminotransferases of HIV Positive Patients Co-Infected With Hepatitis B Virus As Seen At The University Of Abuja Teaching Hospital: A 10 Year Retrospective Study.
Introduction: Hepatitis B virus infection and HIV infection are both endemic in Sub-Saharan Africa and both have similar routes of transmission. Our aim was to determine the prevalence of HIV/HBV co-infection at the Univ...
Comparative Evaluation of Accuracy of Two Electronic Apex Locators In The Presence Of Various Irrigants: An In Vitro Study
The purpose of this study was to compare the accuracy of Raypex 6 electronic apex locator (EAL), with actual root length and with the root length determined by a more commonly used EAL, the ProPex II. An additional objec...
Comparison between Roux-en-Y and Duodenal-jejunal Bypass on hyperglycemia improvements in SD rats
Background：To treat Type 2 diabetes mellitus (T2DM), metabolic surgery which Roux-en-Y gastric bypass (RYGB) and Duodenal-jejunal bypass (DJB) are reported to induce significant improvements on hyperglycemia. In this st...