Efficacy of Dexmedetomidine as an adjutant to Levobupivacaine for Supraclavicular Brachial Plexus Block
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 9
Abstract
Background and Aims: This prospective, randomised double blind study was conducted to establish the effects of addition of dexmedetomidine to levobupivacaine for supraclavicular brachial plexus block. Methods and Material: Sixty patients of ASA I&II, scheduled for upper arm surgery under supraclavicular block were enrolled to receive either 30 ml levobupivacaine 0.5% and 1 ml sodium chloride (Group I) OR 30 ml levobupivacaine 0.5% and 1 ml dexmedetomidine 100 microgram (Group II). Block was performed using nerve locator. The onset of sensory and motor block, duration of block and analgesia, VAS score and time of first rescue analgesia, haemodynamic variables and any side effects were monitored. Results: Demographic data was comparable between the groups. Sensory block onset time was 10.54±2.333 min in group I and 3.24±0.951 min in group II; motor block onset time was 12.21±2.529 min in group I and 3.83±1.197 min in group II; sensory block duration was 7.79±2.007 hours and 16.31±2.606 hours in group I and II respectively; motor block duration was 9.18±1.701 hour in group I and 17.52±2.098 hour in group II; time of first analgesic requirement was longer in group II than in group I (p<0.05). Intraoperative HR and BP were significantly lower in group II as compared to group I (p<0.05). Bradycardia was observed in one patient in group II with no other adverse effects in either of the groups. Conclusions: Hence, addition of dexmedetomidine to levobupivacaine for supraclavicular block significantly prolonged the duration of postoperative analgesia with added advantage of conscious sedation, haemodynamic stability with minimal side effects.
Authors and Affiliations
Dr. Mallika Mohindra, Dr. Anupama Gupta
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