Efficacy of high-flow nasal cannula on acute exacerbation of chronic obstructive pulmonary disease: A meta-analysis
Journal Title: Medical Data Mining - Year 2019, Vol 2, Issue 4
Abstract
Objective: To systematically evaluate the efficacy and feasibility of high-flow nasal cannula (HFNC) on patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods: Systematic searches on PubMed, Web of Science, the Cochrane Library, Embase, CBM (Chinese Biomedicine Database), CNKI (China National Knowledge Infrastructure), Wanfang Database and VIP were performed for randomized controlled trials (RCTs) which explored the effects of HFNC on patients with AECOPD. The retrieval time was from the establishment of each database to July 2019. RevMan5.3 software was used for statistical analysis. Results: A total of 12 articles were included, involving 812 patients. The results showed that: (1) Compared with conventional oxygen therapy, HFNC could improve patients' arterial partial oxygen pressure (PaO2) (MD = 12.70, 95% CI (7.00,18.40), Z = 4.37, P < 0.0001), reduce partial arterial blood carbon dioxide (PaCO2) (MD = -10.99, 95% CI (-14.42, -7.55), Z = 6.26, P < 0.00001) and reduce endotracheal intubation rate (OR = 0.19, 95% CI (0.04, 0.93), Z = 2.05, P = 0.04), shorten the hospitalization time (SMD = -0.74, 95% CI (-1.11,-0.37), Z = 3.95, P < 0.0001). (2) Compared with non-invasive positive pressure ventilation, it has fewer adverse reactions (OR = 0.18, 95% CI (0.09, 0.35), Z = 5.08, P < 0.00001) and shorter hospital stay (SMD = -0.57,95% CI (-0.90,-0.23), Z = 3.33, P = 0.0009). Conclusion: HFNC can improve the patients’ hypoxia symptoms and CO2 retention, reduce the rate of tracheal intubation, and alleviate adverse reactions. However, Limited by the quality and region of the included studies, more high-quality are needed to test it.
Authors and Affiliations
Ying-Ming Sun1, Min Zhang1, Na Sun1, Zhi Guan1, Ying Wang2*
Keywords
Related Articles
- EP ID EP710390
- DOI -
- Views 36
- Downloads 0
Effects of Pilates exercise on balance, walking and lower limbs motor function in stroke patients: A meta-analysis
Objective: To systematically evaluate the effects of Pilates exercise on balance, walking and lower limbs motor function in stroke patients. Methods: The literature databases such as the Cochrane Library, EMbase, PubMed,...
A study on the rule of Chinese medicine use against influenza virus based on data mining
Background: To summarize the rules of the use of traditional Chinese medicine against influenza virus in the high-quality literatures of core journals, and to provide guidance for the prevention and treatment of influenz...
Meta-analysis of Integrated Traditional Chinese and Western Medicine in Treating H Type Hypertension
Objective: The aim of this study was to compare the clinical emcacy of integration of traditional Chinese medicine (TCM) and we stern medicine, and the western medicine therapy for H type hypertension. Methods: The rando...
Association rules analysis of Fufang Kushen injection in combination with traditional Chinese medicine or modern medications in treating Cervical cancer: real-world retrospective study
Objective: The present study aimed to analyze the association rules of Fufang Kushen injection in combination with other traditional Chinese medicine (TCM) or modern medications in treating cervical cancer (CC) based on...
The research progress of acupuncture and moxibustion in the treatment of peripheral facial paralysis
As a common and frequently-occurring disease in clinic, peripheral facial paralysis is worth paying attention to. In fact, as one of the methods for the treatment of peripheral facial paralysis, acupuncture has been wide...