Efficiency of the combination of physical therapy modalities with topical nonsteroidal anti-inflammatory drugs for treatment of pain in rheumatology
Journal Title: Medicina bolu - Year 2018, Vol 3, Issue 1
Abstract
Pain is the most common syndrome in rheumatology. NSAIDs are often used in its treatment. But they have limitations associated with side effects. An advantage of topical drugs and physical factors (electrophoresis, phonophoresis) combination is the use of low doses of the drug and a decrease in time, to achieve a therapeutic effect, reduce the risk of adverse reactions, increase the concentration of the drug in the inflammation focus, prolonged action (creating a drug depot in tissues). Ketoprofen gel (“Artrocol gel”) is one of the representatives of this pharmacological group. Physicochemical properties help ketoprofen to penetrate easily through the skin and create a therapeutic concentration in the underlying tissues. Objective. To assess the effectiveness of ketoprofen gel (“Arthrocol gel”) electrophonophoresis in the treatment of pain in rheumatological patients. Materials and methods. The study was carried out on the basis of Physiotherapy Department of Vinnytsia Regional Clinical Hospital named after M. I. Pirogov. All patients treated according to the unified clinical protocols were divided into experimental group (EG) and control group (CG). Patients of EG (98 persons) underwent electrophonophoresis with ketoprofen gel once a day for a week. In CG (43 persons) ketoprofen gel was used without electrophonophoresis. The intensity of the pain syndrome is monitored using a visual analog scale (VAS) of Huskisson at rest and during movement. A week later, the patient and the doctor evaluated satisfaction with the results of treatment on the scale: not effective, insufficient, satisfactory, good, excellent. Results. There was a persistent decrease in the intensity of pain syndrome in patients of both groups. The VAS scores were lower in the EG starting from the 3rd day of treatment. The intensity of the acute pain syndrome after 1-week treatment at rest (t = 4.71, p < 0.001) and during the movement (t = 3.84, p < 0.001) more decrease in EG. Satisfaction with the results of treatment was higher in EG.
Authors and Affiliations
O. A. Kapeltsova, O. V. Dolynna, N. V. Shkolina
Keywords
Related Articles
- EP ID EP301378
- DOI 10.31636/pmjua.v3i1.87
- Views 117
- Downloads 0
Epidural infiltration of glucocorticoids and local anesthetics in the treatment of non-specific back pain
Background. Non-specific low back pain (NLBP) is the most common complaint following minor injuries and acute respiratory diseases and the leading cause of limiting physical activity in patients younger than 45 years. T...
The use of port-systems of permanent venous access for the control of pain in children
The article deals with the use of long-term venous access and the rationale for its use in pain medicine. It is known that, protein-energy deficiency, previous blocks of chemotherapy, previous multiple venipunctures of p...
Обґрунтування використання методу преемтив-анальгезії ацетамінофеном для періопераційного знеболення у дітей
У структурі післяопераційного знеболення у дітей, як і в інших вікових групах, основне місце займають наркотичні анальгетики, шлях уведення традиційний – внутрішньом’язовий. Метою нашого дослідження було підвищення ефект...
Theories of pain, up to Descartes and after neuromatrix: what role do they have to develop future paradigms?
The article represents a synthesis of literature about antique, medieval and modern pain theories. In short there are described the most relevant theories about nociception and pain. Chronologically there are presented t...
Клинический случай послеоперационного обезболивания пациента путем использования субнаркотических дозировок кетамина при тяжелой абдоминальной патологии
Боль является неизбежным следствием хирургических вмешательств у детей, приводит к большому стрессу и дискомфорту не только для пациентов, но и для их родителей. Интенсивность боли зависит не только от уровня травмы посл...