Emergence of ‘Super Bug’ and Use of Antibiotics: What We Learned, What We Have Yet to Learn?
Journal Title: Journal of Pharmacy Research - Year 2011, Vol 4, Issue 7
Abstract
Recent reports on emergence of a multidrug resistant ‘superbug’ have given the world a warning call against irrational use of antimicrobials. Few examples of most dangerous bugs include MRSA, Klebsiella Penumonia, vancomycin resistant Staphylococcus aureus (VRSA), vancomycin-insensitive Staphylococcus aureus (VISA), vancomycin-resistant enterococcus (VRE). A new candidate in this family of superbugs is New Delhi metallo-ß-lactamase 1 (NDM-1). This review shades a light on various factors related to physician, pharmacist, government, and patient. In addition to these, we also tried to present the corrective strategies that can be useful to curb this globa l health issue. These includes importance of post graduate and continuing medical education, level-of-use prescribing restrictions, avoidance of financial incentives on the basis of drug sale, essential drugs list and national formulary, antibiotic order form, automatic stop orders etc. To curb the antibiotic we need to increase awareness and surveillance of antibiotic resistance, improve and regulate antibiotic use in humans as well as in animals, encourage new antimicrobials development, and increase funding for surveillance, research and education.
Authors and Affiliations
Reema Thomas* and Mukesh Nandave
Keywords
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