EMULGEL: A COMPREHENSIVE REVIEW ON THE RECENT ADVANCES IN TOPICAL DRUG DELIVERY
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 11
Abstract
Emulgel has emerged as a promising drug delivery system for the delivery of hydrophobic drugs. When gel and emulsion are used in combined form they are referred as Emulgel. Emulsion in gel have emerged as one of the most interesting topical drug delivery system as it have dual release control system i.e. emulsion and gel. Gels are relatively newer class of dosage form created by entrapment of large amount of aqueous or hydro alcoholic liquid in a network of colloidal solid particles which may consist of inorganic substances or organic polymers of natural or synthetic origin. In recent years there has been great interest in the use of novel polymers with complex function such as emulsifiers and thickeners. The gelling capacity of these compounds allows the formulation of stable emulsion and creams by decreasing surface and interfacial tension at the same time increasing the viscosity of aqueous phase. In spite of many advantages of gels a major limitation is in the delivery of hydrophobic drug. So to overcome this limitation an emulsion based approach is being used so that even a hydrophobic moiety can enjoy the unique property of gel.
Authors and Affiliations
Baibhav Joshi , Gurpreet Singh , A. C Rana , Seema Saini , Vikas Singla
CLINICAL PRESENTATION AND ASSOCIATION AMONG TUBERCULOSIS PATIENTS; COHORT COMPARISON BETWEEN SMOKERS VERSUS NEVER-SMOKE IN PENANG, MALAYSIA
We aimed to compare the demographic and clinical characteristics with risk determination of TB patients who were smokers vs. non-smokers. The retrospective, observational & cross-sectional cohort survey was done to c...
VIRTUAL TOXICITY STUDIES OF NOVEL 1,4-DIHYDROPYRIDINE DERIVATIVES
Virtual toxicity of N3, N5-diphenyl-1,4-dihydropyridine-3,5-dicarbohydrazides [2A-2D’] and 2,6-dimethyl-1,4-dihydropyridine-3,5-yl-bis[carbonyl-2-(phenyl)]pyrazolidine-3,5-diones] [3A-3D’] were extensively studied. Compu...
DEVELOPMENT AND VALIDATION OF METHOD FOR DETERMINATION OF CICLESONIDE IN (MICRONIZED) BY HPLC
A simple, selective and rapid reversed phase high performance liquid chromatographic (RPHPLC) method for the analysis of Ciclesonide has been developed and validated. The separation was achieved from HPLC Column (Waters...
FORMULATION AND DEVELOPMENT OF TOPICAL NIOSOMAL GEL OF BCS CLASS - III ANTI-VIRAL DRUG FOR BETTER EFFICACY AS HERPES TREATMENT
The objective of present research work was to formulate niosomal gel of ACV and to evaluate it for enhancements of skin permeation and skin retention characteristics. ACV niosomes were prepared by classical thin layer hy...
PHYTOCHEMICAL AND CLINICAL EVALUATION OF SARIBA (HEMIDESMUS INDICUS) ON WOUND HEALING
Present study was carried out to screen the phyto-chemical and clinical evaluation of wound healing property of Sariba (Hemidesmus indicus) root paste on chronic wounds. Physico-chemical analysis of Hemidesmus indicus li...