Epidemiology and Morphological Features of Thyroid Cancer in People Living in Vinnytsia Region
Journal Title: Міжнародний ендокринологічний журнал - Year 2016, Vol 7, Issue 79
Abstract
Background. Thyroid cancer (TC) is the most common tumor of the endocrine glands. The problem of thyroid cancer in Ukraine went far beyond the consequences of the Chernobyl disaster and is characterized by increasing morbidity of this pathology. Objective: to study the morbidity of thyroid cancer in Vinnytsia region. Materials and methods. The dynamics of thyroid cancer for the last 30 years (1986–2015) among the residents of Vinnytsia region was assessed. Results. The analysis of thyroid cancer rate for 30-year period shows its steady growth, especially for the last 10 years. The morbidity in the pre accident period ranged 1.0–1.2 cases per 100 thousand population; the first 10 years after the accident, it grew up to 2.2–2.8, in 2001–2005 it increased to 4.4–5.5 cases per 100 thousand population, and in recent years 9.9–11.3 cases per 100 thousand population. When compared morbidity in Vinnytsia region with the republic data, these indicators in region are more higher than in the whole Ukraine, but much less than in the regions most affected by the Chernobyl disaster (Kyiv region, city of Kyiv). In the region the morbidity significantly prevails among women compared to the male population. The analysis of the dynamics of thyroid cancer rate in different age groups did not demonstrate statistically significant differences. Conclusions. The researches of thyroid cancer structure among the residents of Vinnytsia region showed a strong growth of the diseases rate in adult patients. The level of the region morbidity exceeds republican date and tends to increase, with highly differentiated forms prevail which are characterized by mildly aggressive course, mostly in women, in solitary nodes less than 20 mm. That should arouse oncologic alertness in these patients.
Authors and Affiliations
A. V. Palamarchuk, M. V. Vlasenko, P. G. Prudius, V. M. Kolomiets
Pharmacotherapeutic efficiency and advantages of the combined treatment of patients with type 2 diabetes mellitus
Background. The early prescription of a combination of extended-release metformin with glimepiride influencing different links of the pathogenesis of type 2 diabetes mellitus (DM) is grounded in the article. The purpose...
Diabetes Mellitus: New Views and Old Delusions. Part 2. Pevention of Diabetes Mellitus Type 2
No abstract
New Opportunities for Diabetes Mellitus Treatment
The paper presents the results of the study of the efficiency and safety of the insulins Insuman® Rapid, Insuman® Basal, Insuman® Comb 25 in patients with type 2 diabetes mellitus. Those medications were found to have hi...
Diabetes mellitus and atherosclerosis. The role of inflammatory processes in pathogenesis (literature review)
The review of the literature summarizes and analyzes the material on inflammatory processes accompanying cardiovascular complications in diabetes mellitus. The role of endothelial dysfunction is shown leading to an incre...
DNA fragmentation in spermatozoa of men with infertility (literature review)
In the literature review, data are analyzed on the violation of sperm DNA fragmentation and mechanisms of damage to DNA integrity in infertile men. The basic theories of molecular mechanisms of DNA damage and sperm chrom...