Erythrophagocytosis in Bone Marrow: A Clue to Pyrexia of Unknown Origin

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Erythrophagocytosis in Bone Marrow: A Clue to Pyrexia of Unknown Origin

Journal Title: Journal of Microbiology and Infectious Diseases - Year 2018, Vol 8, Issue 2

Abstract

Erythrophagocytosis in Bone Marrow: A Clue to Pyrexia of Unknown Origin Neha Garg, Surabhi Raina, Mrinalini Kotru, Meera Sikka Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India ABSTRACT Bone marrow (BM) is usually done to investigate the patients for Pyrexia of Unknown Origin (PUO). However, only 16.5 % of cases reveal any diagnostic information. Increasing incidence of atypical presentations is seen in typhoid. Careful examination of BM to pick up clues for diagnosis is important. We report a case of a 15 year old female who presented with fever associated with altered sensorium, gum bleeding and loose stools. Hematological findings revealed pancytopenia with macrocytic anemia with erythrophagocytosis in BM aspirates. A diagnosis of typhoid was made with a positive typhi dot IgM. The authors present this case to highlight the importance of simple BM findings of erythrophagocytosis and how awareness about this feature can point towards the right diagnosis in the midst of atypical clinical and hematological features. J Microbiol Infect Dis 2018; 8(2):73-75

Authors and Affiliations

Neha Garg, Surabhi Raina, Mrinalini Kotru, Meera Sikka

Keywords

Extended Spectrum β-lactamases and antimicrobial susceptibility among clinical isolates of Pseudomonas aeruginosa in the West Bank, Palestine

Objectives: Class D oxacillinases are frequently acquired by gram negative bacteria in general and P. aeruginosa in particular. P. aeruginosa is commonly implicated in causing nosocomial infections. The evolution of ant...

EP ID EP480572
DOI 10.5799/jmid.434605
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