Erythrophagocytosis in Bone Marrow: A Clue to Pyrexia of Unknown Origin
Journal Title: Journal of Microbiology and Infectious Diseases - Year 2018, Vol 8, Issue 2
Abstract
Erythrophagocytosis in Bone Marrow: A Clue to Pyrexia of Unknown Origin Neha Garg, Surabhi Raina, Mrinalini Kotru, Meera Sikka Department of Pathology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India ABSTRACT Bone marrow (BM) is usually done to investigate the patients for Pyrexia of Unknown Origin (PUO). However, only 16.5 % of cases reveal any diagnostic information. Increasing incidence of atypical presentations is seen in typhoid. Careful examination of BM to pick up clues for diagnosis is important. We report a case of a 15 year old female who presented with fever associated with altered sensorium, gum bleeding and loose stools. Hematological findings revealed pancytopenia with macrocytic anemia with erythrophagocytosis in BM aspirates. A diagnosis of typhoid was made with a positive typhi dot IgM. The authors present this case to highlight the importance of simple BM findings of erythrophagocytosis and how awareness about this feature can point towards the right diagnosis in the midst of atypical clinical and hematological features. J Microbiol Infect Dis 2018; 8(2):73-75
Authors and Affiliations
Neha Garg, Surabhi Raina, Mrinalini Kotru, Meera Sikka
Keywords
Related Articles
- EP ID EP480572
- DOI 10.5799/jmid.434605
- Views 119
- Downloads 0
Brucella spondylodiscitis: Multifocal involvement in thoracic and lumbar areas; a rare case
Brucellosis is a zoonosis that can affect many organs or systems. Musculoskeletal system is the most commonly affected site in brucellosis and the frequency of musculoskeletal system involvement varies between 2% an...
Seroprevalence of Leptospira antibodies among populations at risk
Objective: This study was performed to assess the Leptospira IgG antibodies seroprevalence among populations at risk in Hodeida Governorate, Yemen. Methods: A total of 200 subjects (136 males and 64 females) participate...
Prevalence and risk factors of extended-spectrum β-lactamases producing Enterobacteriaceae in a general hospital in Saudi Arabia
Objective: To estimate the prevalence and associated risk factors of extended-spectrum β-lactamase producing Enterobacte riaceae (ESBL) in King Khaled General Hospital, Saudi Arabia. Methods: A twelve -month retrospecti...
Sentetik insan katyonik antimikrobiyal peptidi olan hCAP-18/LL37’nin idrar yolu patojenlerine karşı anti-biyofim aktivitesi ve öldürücü etkinliği
Amaç: Cathelicidin LL37 mesane epitel hücrelerinin kimyasal bir savunma komponenti olup antimikrobiyal peptitler arasında idrar yolunda bakterilerin yapışmasını engelleyerek mukozal bağışıklıkta önemli bir role sahiptir....
Susceptibility of Minocycline against Carbapenem Resistant Gram-Negative Bacilli
Susceptibility of Minocycline against Carbapenem Resistant Gram-Negative Bacilli Anup R Warrier1; Rachana Babu2 1Department of Infectious Diseases, Aster Medcity, Kochi, Kerela, India 2Department of Microbiology, Aster M...