Ethoxyquin on Haematological and Biochemical Parameters in the Fish, Anabas testudineus (Bloch, 1792)
Journal Title: International Journal of Zoological Investigations - Year 2017, Vol 3, Issue 1
Abstract
Ethoxyquin, a quinoline fungicide, is widely used as an antioxidant in the animal feed industry, and also used as feed constituents, notably in fish meal. Determination of median lethal concentration of ethoxyquin by probit analysis showed LC50 value as 16.5 mg/L. Fish were exposed to one-tenth and one-fifth of LC50-96 h (1.65 and 3.3 mg/L concentration, respectively) for 96 h. Ethoxyquin exposure did not alter the body weights of the animal, however, the percentage of mucous deposition showed a significant (P<0.05) increase at both sublethal concentrations. Fish exposed to ethoxyquin showed significant reduction in serum protein and increase in serum glucose. This could be due to lysis of RBC or catabolism of protein for the immediate release of energy in demand of toxic stress. Increase in the activities of aspartate and alanine aminotransferase may be due the toxic stress induced by ethoxyquin which altered the normal metabolism of animal. Alterations in haematological parameters may be due to haemolysing capacity of ethoxyquin and rapid oxidation of haemoglobin to methaemoglobin due to toxicant exposure. Thus, ethoxyquin at acute exposure of sublethal concentrations induced haematological and biochemical alterations in serum of fish, Anabas testudineus
Authors and Affiliations
Dr. K. C. Chitra
Keywords
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