EVALUATION ACTIVITIES OF CHITOSAN ASCORBATE AGAINST RODS OF HELICOBACTER PYLORI ISOLATED FROM GINGIVAL POCKETS AND ATHEROSCLEROTIC PLAQUES
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2016, Vol 0, Issue
Abstract
The aim of the study was determine activity of chitosan ascorbate against 17 strains of Helicobacter pylori. The strains were isolated from gingival pockets (7 strains), atherosclerotic plaques from carotid and femoral (10 strains). Chitosan was obtained from krill chitin and deacetylation degree was equal 60%. The ratio of ascorbic to chitosan was equal 1. The susceptibility of rods was determined by means of plate dilution technique in Brucella agar with 5% sheep’s blood. The inoculum contained 105 CFU/spot. Incubation was performed in anaerobic jars with Campy Pak (BBL) for 48 hrs. The MIC was interpreted as the lowest concentration of chitosan ascorbate inhibiting the growth of bacteria. The results indicated, that chitosan ascorbate at the lowest concentrations was active against 35% of the strains. The Helicobacter pylori rods isolated from gingival pockets were the highest susceptible than isolated from atherosclerotic plaques.
Authors and Affiliations
Anna Kędzia, Barbara Kochańska, Alina Gębska, Maria Wierzbowska, Andrzej Kufel
Keywords
Related Articles
- EP ID EP190578
- DOI 10.15259/PCACD.21.10
- Views 81
- Downloads 0
INFLUENCE OF A POLYVINYL ALKOHOL AND DEXTRANE ON THE PROPERTIES OF HYDROPHILIC GELS CONTAINING LACTIC ACID COMPLEX WITH CHITOSAN
The investigated preparations on methylcellulose base revealed good adhesion to the vaginal mucosa and were present on it throughout the daily activities of the patient. This property enabled the continuity of 24-hour ac...
PREPARATION OF MICRO AND NANOSTRUCTURES OF CHITOSAN BY ULTRASONIC COALESCENCE OF W/O EMULSIONS
In the paper, the preeliminary study of chitosan micro and nanospheres precipitation due to two reverse emulsions (W/O) coalescence is described. The composition conditions, which must be filled to obtain stable reverse...
CHITOSAN APPLIED FOR GYPSUM MODIFICATION
In order to improve the properties of gypsum materials, including workability, mechanical strength and ability to retain water, various admixtures (also polymers), known as plasticisers, have been applied. These polymers...
BIODISTRIBUTION OF DOXORUBICIN-LOADED SUCCINOYL CHITOSAN NANOPARTICLES IN MICE INJECTED VIA INTRAVENOUS OR INTRANASAL ROUTES
Chitosan (Chi) is an extremely promising natural biopolymer with remarkable potency for the development of drug and vaccine delivery nanosystems. Various Chi derivatives are used to form nanoparticles (NPs) with unique p...
DEVELOPMENT OF FOOD IMPROVING CALCIUM-ENRICHED BIOACTIVE AGENTS PRODUCED FROM CHITINOUS WASTES GENERATED IN THE PROCESS OF AQUATIC ANIMAL PROCESSING
The CHIZITEL chitin-and-mineral complex is obtained from crustacean wastes. The BAA formula helping to facilitate calcium, phosphorus and magnesium fixation in the human body was found to be the result of this study. Thi...