Evaluation of antimicrobial activity of three important medicinal plants of South India
Journal Title: International Journal of Bio-Pharma Research - Year 2019, Vol 8, Issue 1
Abstract
India is found to be a country with rich biodiversity and enormous treasure of herbal plants and consequently called as medicinal garden of the world. Plants are the richest source of natural antimicrobial agents. In recent years drug resistance to human pathogenic bacteria has been commonly reported from all over the world. Therefore, there is a need to develop alternative antimicrobial drugs for the treatment of infectious diseases; one approach is to screen local medicinal plants for possible antimicrobial properties. The present study was designed to evaluate the antimicrobial efficacy of hexane, chloroform and methanol crude extracts of the leaves of three important medicinal plants viz., Biophytum sensitivum (L.) DC, Bougainvillea spectabilis L. and Caesalpinia bonducella (L.) Fleming, collected from in and around Visakhapatnam District. The antimicrobial activity of the crude extracts was tested against three Gram Positive bacteria (Bacillus subtilis MTCC 441, Enterococcus faecalis MTCC 439, Staphylococcus aureus MTCC 737), Three Gram Negative bacteria (Escherichia coli MTCC 443, Proteus vulgaris MTCC 426 and Pseudomonas aeruginosa MTCC 1688) and three Fungal strains (Candida albicans MTCC 227, Epidermophyton floccosum MTCC 613 and Trichophyton mentagrophytes MTCC 7687) using agar well diffusion assay. Our results demonstrated that methanol extracts of these plants leaves have concentration dependent antibacterial activity against some of the tested organisms. Further studies should be undertaken to elucidate the exact mechanism of action of antimicrobial effect to identify the active ingredients which can be used for drug development program.
Authors and Affiliations
Gopalakrishnaiah B. , Aniel Kumar O.
Keywords
Related Articles
- EP ID EP500067
- DOI 10.21746/aps.2018.8.1.1
- Views 118
- Downloads 0
Performance of Solar cell fabricated using TiO2: rGO on glass and Si substrates prepared by Thermal Evaporation Technique
TiO2: rGO doped material is deposited on glass and Si substrates. These hetero nanostructures have multiple applications in photovoltaic because of their charge transport properties. In this study, we prepared tetragonal...
Effect of vagbhattokta tambula sevana as per ayurveda on mukha roga
The diseases of oral cavity termed as Mukharoga in Ayurveda which involve various pathological conditions such as; Danta Gata Roga and Austha Gata Roga etc. Ayurveda described that Mukharogas may occur at different site...
Clinical efficacy of Ashwattha Choorna Lepa in the management of Mukhapaka
Mukha (mouth) is one of the important parts of body and it is exposed to various risk factors due to the bad habits like tobacco chewing and smoking etc. Mukhapaka is pathological condition related to Mukha which occurs...
Development and Biopharmaceutical Characterization of BCS Class II Drug – Naproxen by Two Way Complexation Solid Dispersion Technique
The objective of this study was to increase the solubility and bioavailability of Naproxen (NP) by fabricating ternary solid dispersion (tSDs) with water soluble polymer PEG 6000 and crospovidone. tSDs were prepared and...
Development and optimization of Etoposide loaded nanoparticles by using DoE response surface central composite design
Cancer is a leading cause of death globally. The World Health Organizationestimates that 9.6 million people died of cancer in 2018. More than 70% of all cancer deaths occur in low- and middle-income countries, where res...