Evaluation of BAL versus sputum specimen for the diagnosis of pulmonary tuberculosis in sputum AFB smear negative patients- retrospective study at PIMSR, Gujarat
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 3
Abstract
Aims and Objective Early diagnosis of smear negative tuberculosis is a significant challenge in control of tuberculosis The present retrospective study was done on sputum and BAL samples of the same patients for better diagnosis of pulmonary tuberculosisMaterial and Methods A total of 1000 700 sputum and 300 BAL specimens were processed to rule out tuberculosis in suspected cases during the period of August 2015 to March 2018 The result of sputum as well as BAL specimens from 300 same patients were examined for ZN staining and GeneXpert tests The samples of sputum and BAL were processed as per the standard guidelinesResults Total of 1000 specimens 700 sputum 300 BAL were considered for the results Out of 1000 specimens 300 patients had submitted both sputum as well as BAL specimens These 300 specimens were analyzed for comparative resultsOut of 300 common samples 109 363 sputum and 136 45 BAL samples are positive by ZN stain Whereas Out of 300 common samples 149 496 sputum and 170 566 BAL samples are positive by GeneXpert method Out of 149 common specimens that were positive by GeneXpert 533 were found to be Rifampicin resistantConclusion Incidence of MDR TB is 33 in our hospital BAL was found to be superior specimen to sputum for the diagnosis of ZN smears negative pulmonary TB Sensitivity and specificity of GeneXpert is higher than AFB smear microscopyKeywords Sputum BAL GeneXpert MDRTB Multidrug Resistance Tuberculosis
Authors and Affiliations
Mohmed Soeb Jankhwala, Vaidehi J. Mehta, Anant Marathe
Keywords
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- EP ID EP485864
- DOI 10.18231/2581-4761.2018.0032
- Views 71
- Downloads 0
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