A study of intestinal parasitic infections in HIV infected individuals in Puducherry
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 4
Abstract
Introduction Human immuno deficiency virus infection has become a pandemic Infection with HIV results in a chronic illness characterized by a progressive decline in cellmediated immune function Diarrhoea occurs in almost 90 of patients with HIV in developing countries at sometime during the clinical course and is the presenting symptom of approximately one third of patients with HIV infectionAims To find out the common enteric parasitic pathogens in the HIV infected individuals To correlate the immune status to the parasitic infection To find out the symptomatic correlation to the pathogensSettings and Design The cross sectional study was carried out in Puducherry for a period of 15 monthsMaterials and Methods Two consecutive stool samples were collected from from HIV seropositive patients The samples were concentrated and subjected to stool concentration iodine and saline mounts Kinyouns stainingStatistical analysis used Epi info 6 computer software package CDC Atlanta Georgia USA 1995Results Of the 22 diarrhoeic stools of HIV cases 7318 yielded parasites on Kinyouns staining all 7100 were opportunistic protozoan pathogens The prevalence of intestinal parasites among the HIV infected patients is as follows Cryptosporidium sp and Microsporidium sp each were found in 63 of HIV seropositive cases Strongyloides was seen in 25 of 80 seropositive cases The mean CD4 counts in cases with parasites are listed as follows Cryptosporidium sp1332 cells Microsporidium sp896 cells Strongyloides stercoralis2285 Entamoeba histolyticadispar522 cells Giardia sp 884 cells Cryptosporidium sp and Strongyloides stercoralis are found more in HIV seropositive cases with CD4 counts less than 200 cells p0002 OR36 95 CI456 for Cryptosporidium sp and OR146 95 CI15396 for Strongyloides stercoralis There is a significant correlation between CD4 counts Conclusions The present study shows that Cryptosporidium is the predominant enteric protozoan parasiteKeywords HIV Diarrhoea Cryptosporidium Kinyoun staining CD4 countsKey Messages Enteric parasitic pathogens opportunistic in HIV infected individuals is common in patients with normal CD4 counts and antibiotic prophylaxis
Authors and Affiliations
Hemalatha G. , Mangaiyarkarasi T. , Malini A. , Sageera Banoo, Sethmadhavan K.
Keywords
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- EP ID EP485891
- DOI 10.18231/2581-4761.2018.0057
- Views 99
- Downloads 0
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