Evaluation of behavioral and neuroprotective activity of Curcuma amada against cell phone radiation induced brain damage in rats
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2015, Vol 3, Issue 6
Abstract
Cell phone radiation is a well-known neurotoxic agent and neurodamage induced by cell phone radiation (Frequency range of 900 MHz) is one of the model systems for the screening of neuroprotective activity of plant extracts. Damage begins with the changes in behaviour, loss of enzymes. The present study was focused to evaluate the behavioural and neuroprotective activity of Curcuma amada (100, 200, 300 mg/kg) against cell phone radiation. Behavioural study were analysed by using Y maze. Hydro alcoholic extract of Curcuma amada were compared for its neuroprotective activity with control group. Curcuma amada 300mg/kg had shown significant behavioural and neuroprotective activity on par with 100 mg/kg. Curcuminoids and flavonoids responsible for neuroprotective activity of Curcuma amada.
Authors and Affiliations
Veena V, Janarthan M, Varaprasad Saka, Revana Siddappa D, Shaik Jilani, Shaik Rabbani Basha,Gowtham Kumar. K
Keywords
Related Articles
- EP ID EP33352
- DOI -
- Views 253
- Downloads 0
A review of various analytical methods on Atrovastatin
There is a review of analytical methods for atorvastatin, such as spectrophotometry, derivative spectrophotometry and various chromatographic procedures such as, high-performance liquid chromatography (HPLC), high-perf...
Formulation, characterization and evaluation of zidovudine controlled release matrix tablets using HPMC K4M and K100M
The aim of present investigation is preparation, characterization and evaluation of oral controlled release matrix tablets of Zidovudine (AZT) in order to improve efficacy and reduce its side effects. FTIR and DSC conf...
Phytochemical profile of three selected plants of Acalypha hispida, Acalypha nerifolia and Acalypha fruiticosa
A Photochemical profile of three selected plant species Acalypha hispida, Acalypha nerifolia and Acalypha fruiticosa were carried out. Crude dry powder analysis, ash value, solubility, extractive value, fluorescence an...
Effects of genotype, soil and technological treatment on chemical composition and antioxidant activity of cocoa beans produced in Cote dIvoire
Consumption of cocoa products has recently increased due to its organoleptic qualities and potential benefits to human health. To meet this demand without compromising the activity in the sector for future generations,...
Design and development of Metformin hydrochloride Trilayered sustained release tablets
Diabetes is one of the major causes of death and disability in the world. Diabetes results from decreased secretion of insulin, decreased insulin action or both. The main aims of the investigation was to design and dev...