Evaluation of behavioral and neuroprotective activity of Curcuma amada against cell phone radiation induced brain damage in rats
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2015, Vol 3, Issue 6
Abstract
Cell phone radiation is a well-known neurotoxic agent and neurodamage induced by cell phone radiation (Frequency range of 900 MHz) is one of the model systems for the screening of neuroprotective activity of plant extracts. Damage begins with the changes in behaviour, loss of enzymes. The present study was focused to evaluate the behavioural and neuroprotective activity of Curcuma amada (100, 200, 300 mg/kg) against cell phone radiation. Behavioural study were analysed by using Y maze. Hydro alcoholic extract of Curcuma amada were compared for its neuroprotective activity with control group. Curcuma amada 300mg/kg had shown significant behavioural and neuroprotective activity on par with 100 mg/kg. Curcuminoids and flavonoids responsible for neuroprotective activity of Curcuma amada.
Authors and Affiliations
Veena V, Janarthan M, Varaprasad Saka, Revana Siddappa D, Shaik Jilani, Shaik Rabbani Basha,Gowtham Kumar. K
Keywords
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