Evaluation of diagnostic accuracy of FNAC and correlation with histopathology in thyroid lesions
Journal Title: Pathology Update: Tropical Journal of Pathology and Microbiology - Year 2017, Vol 3, Issue 2
Abstract
Aim: The aim of the study is to evaluate the accuracy of FNAC diagnosis in non neoplastic & neoplastic lesions of thyroid, and correlating with histopathological findings. Materials and Methods: This was a prospective study done in department of Pathology, Tagore medical college for a period of 3 years. 115 cases of thyroid subjected to FNAC where histopathology diagnosis was available were included in the study. The correlation of FNAC diagnosis with histopathology was made and the results were analysed. Results: The range of the age of the patient in this study was 25 to 60 years. The male to female ratio was 18.5:81.5. The maximum cases were colloid goitre (59.2%) in which 12.5% were with features of papillary hyperplasia. Occurrences of dual pathology were seen in our study with one case of Hashimoto’s thyroiditis with focus of papillary carcinoma and the other was medullary carcinoma with papillary carcinoma. 2 cases of anaplastic thyroid carcinoma were also seen. Conclusion: In our study sensitivity of FNAC in detecting thyroid lesions was 93.75%, and the specificity was 97.01%. FNAC of thyroid had a diagnostic accuracy of 95.65% which clearly indicates that FNAC can be used as non invasive, cost effective and a safe diagnostic method for defining thyroid disorders.
Authors and Affiliations
C. P. Luck, Jamunarani Srirangaramasamy, Madasamy Balamurugan, Balaji Arumugam, Aruna padmavathy, Revathy Revathy
Keywords
Related Articles
- EP ID EP263188
- DOI 10.17511/jopm.2017.i2.03
- Views 138
- Downloads 0
Microfilaria in fine needle aspiration smears of neoplastic lesions: a case series
Filariasis is a major public health problem in south East Asia including India. It is transmitted by bite of culex mosquito and most commonly caused by Wauchereria bancrofti. Conventional mode of diagnosis is demonstrati...
Pancytopenia: A multidisciplinary assessment of hemato-etiological and clinical spectrum in a tertiary care hospital
Background: The causes of pancytopenia range from simple, completely treatable diseases to serious life-threatening conditions. A thorough evaluation of these cases is mandatory as it would benefit the patients to receiv...
Significance of histologic grading using visual analogue scale in chronic gastritis
Introduction: Helicobacter Pylori and its association with carcinogenesis has significantly changed the field, establishing new guidelines for the detection of it. Carcinogenicity of H. Pylori necessitates grading the va...
Hemorrhagic Fever Viruses
Viruses causing hemorrhagic fever are broadly classified into five families as Arenaviridae, Bunyaviridae, Filoviridae, Flaviviridae & Rhabdoviridae. Some of them like Ebola virus can spread through aerosols and are cons...
Prostate cancer diagnosis by detection of uPM3 in urine
Background: The widespread acceptance of serum PSA testing for the early detection of prostate cancer has been hampered by the low specificity and unnecessary biopsies. Methods: This study was carried out to detect prost...