Evaluation of hepatoprotective and antioxidant activity of Merremia turpethum
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2014, Vol 3, Issue 4
Abstract
The present study was carried out to evaluate the hepatoprotective and antioxidant effect of the methonalic extract of Merremiaturpethum(MEMT) in Wistar albino rats. Protective action of MEEC was evaluated using animal model of hepatotoxicity induced by acetaminophen (2 g/kg). Liver maker enzymes were assayed in serum and antioxidant status was assessed in liver tissue. Histopathology was also studied. Levels of aspartate aminotransferase (AST), alanine aminotransferace (ALT), alkaline phosphatase (ALP) and total bilirubin were increased and the levels of total protein were decreased in acetaminophen treated rats. The potency of methanol extract of the plant showed rich antioxidant properties.From this study it can be concluded that the (MEMT) showed significant hepatoprotective and antioxidant action.
Authors and Affiliations
Dr. Shankara sharma
Keywords
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