Abstract

The aim of current study was evaluate the anthelmintic activity of petroleum ether, chloroform & methanol extracts of roots and leaves of pavetta indica linn. (Rubiaceae) against Indian adult earthworms (Pheretima posthuma) and roundworm (Ascaridia gali). The parameters like the time of paralysis and the time of death were determined by using the different extract at different concentration (25, 50, and 100 mg/ml). Albendazole (in 5% aqueous DMF) was used as reference standard and 5% aqueous in DMF as a control group. Higher activities were observed at the higher concentration. Dose dependent activity was observed in all extracts. The shortest time required for paralysis and death was observed with concentration of 100 mg/ml of methanol extract of roots of plant. The studies indicate that the root extract of plant exhibited more potent activity as compared to leaves extracts.

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