EVALUATION OF PREPARATIONS PHARMACEUTICAL SALAZOSULFAPIRIDIN DEPENDING USED FOOD SUPPLEMENTS CONTAINING CHITOSAN IN MODEL “IN VITRO”
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2011, Vol 0, Issue
Abstract
An increase in sulfasalazine absorption on a polymer at increasing pH from 7.6 to 8.0 may be explained by the swelling properties of chitosan, which forms a conglomeration in the form of emulsion system. Basing on the above considerations, it may be assumed that an antagonistic interaction occurs between the investigated drug and the polymer, which consists in absorption of the drug on a polymer such as chitosan.
Authors and Affiliations
Jan Meler, Bożena Grimling, Janusz Pluta
Keywords
Related Articles
- EP ID EP73674
- DOI -
- Views 77
- Downloads 0
CHARACTERIZATION OF WATER STATE IN CHITOSAN HYDROGEL MEMBRANES
In this study, the structure of hydrogel chitosan membranes was investigated. To determine the structure of hydrogel membranes the Differential Scanning Calorimetry (DSC) was used. On the basis of DSC spectra the enthalp...
CHARACTERISATION OF THIN CHITOSAN FILMS FOR GUIDED TISSUE REGENERATION PURPOSES
The morphology and structure of thin films containing chitosan (Ch) with montmorillonite (MMT) were characterised by scanning electron microscopy (SEM), atomic force microscopy (AFM) and attenuated total reflectance Four...
Physicochemical properties of chitin-protein complex from shell of RED KING crab (Paralithodes camtchaticus) at various stages of molting cycle
It is worth of note that the studies have shown the substantial differences in the physicochemical characteristics of the chitin-protein complex isolated from the crab shell at various stages of the molting cycle. Perhap...
LARGE SIZE DNA IN VITRO AND IN VIVO DELIVERY USING CHITOSAN TRANSFECTION
In modern medicine, many diseases can be treated using gene therapy, which requires a DNA delivery system to prevent DNA from degradation and to transport it to the cells. Liposomal reagents are expensive for such a ther...
VISCOMETRIC STUDIES OF MICROCRYSTALLINE CHITOSAN/POLY(VINYL ALCOHOL) MIXTURES
In the present paper, the results of viscosity measurements in dilute solutions of microcrystalline chitosan (MCCh) with poly(vinyl alcohol) (PVA) of different degrees of hydrolysis are presented. Microcrystalline chitos...