EVALUATION OF PREPARATIONS PHARMACEUTICAL SALAZOSULFAPIRIDIN DEPENDING USED FOOD SUPPLEMENTS CONTAINING CHITOSAN IN MODEL “IN VITRO”
Journal Title: Progress on Chemistry and Application of Chitin and its Derivatives - Year 2011, Vol 0, Issue
Abstract
An increase in sulfasalazine absorption on a polymer at increasing pH from 7.6 to 8.0 may be explained by the swelling properties of chitosan, which forms a conglomeration in the form of emulsion system. Basing on the above considerations, it may be assumed that an antagonistic interaction occurs between the investigated drug and the polymer, which consists in absorption of the drug on a polymer such as chitosan.
Authors and Affiliations
Jan Meler, Bożena Grimling, Janusz Pluta
Keywords
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- EP ID EP73674
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