Evaluation of Serum Iron and Magnesium levels in Sudanese males Cigarette Smokers in Khartoum State - Sudan
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH IN MEDICAL SCIENCES - Year 2019, Vol 5, Issue 5
Abstract
Background Smoking is an escalating health problem especially in Develop countries such as Sudan. Cigarette smoking lead to the uptake of many hazardous compounds and their metabolites extracted from burning tobacco. The aim of this study to measure the serum Magnesium and Iron levels in Sudanese Males Cigarette Smokers in Khartoum State. Material and Methods The study was designed as cross sectional study, this study was performed in national center for research, during period from April 2018 to August 2018. 75 Sample were collected from Sudanese males cigarette smokers as case group and 75 sample from Sudanese nonsmokers male as control group, the age of the population studied ranged between 20-45 years. Three ml of venous blood sample were collected from both smokers and nonsmokers group into plain containers, using sterile disposable plastic syringe. Data was analysis using SPSS Software version 20. Were measure the serum levels of Magnesium and Iron determined by atomic absorption spectrophotometer (manual part 0303- 0152, release Date September 1996 by the registered trademark of the PerkinElmer inc). Results The mean of serum Magnesium in smokers was (26.5 mg/dl ±3.6) with p-value (0.000), while the mean of serum magnesium in nonsmokers (19.9 mg/dl ±1.9) with p-value (0.000). While the mean of serum Magnesium in age of smokers (20-29 years old) was (26.6 mg/dl±3.7), and the serum Magnesium in age of smokers between (30-45 years old) was (26.3 mg/dl±3.5) with p-value (0.73). While the mean of serum Magnesium in duration of smoking (more than 10 years) was (27.7 mg/dl ±3.7), and the mean of serum Magnesium in duration of smoking (less than 10 years) with p-value (0.12). While the mean of serum Magnesium in number of cigarette per day (1-15 cigarette per day) was (26.4 mg/dl ±3.6), and the mean of serum Magnesium in number of cigarette per day (16-30 cigarette per day) was (27.5 mg/dl ±3.8) with p-value (0.51). The mean of serum Iron in smokers was (0.24 mg/dl ±0.11) with p-value (0.000), while the mean of serum Iron in nonsmokers (0.73 mg/dl ±0.16) with p-value (0.000). While the mean of serum Iron in age of smokers (20-29 years old) was (0.24±0.11 mg/dl), and the mean serum Iron in age of smokers between (30-45 years old) was (0.18 mg/dl ±0.10) with p-value (0.45). While the mean of serum Iron in duration of smoking (more than 10 years) was (0.16 mg/dl± 0.10), and the mean of serum Iron in duration of smoking (less than 10 years) was (0.26 mg/dl ± 0.12) with ±0.10), and the mean of serum Iron in number of cigarette per day (16-30 cigarette per day) was (0.14 mg/dl ±0.11) with p-value (0.01). Conclusion The study conclude that The serum level of Magnesium is high in the smokers group compared with nonsmokers group, and serum level of Iron is low in the smokers group compared with nonsmokers group. There was weak positive correlation between serum Magnesium and Iron with Age of smokers between (20-29 year) and with (30-45 year). There was weak positive correlation between serum Magnesium and Iron with duration of smoking between (more than 10 years) and (less than 10 year). There was weak positive correlation between serum Magnesium with smokers for (1-15 cigarette per day) and with (16-30 cigarette per day). And complete correlation between serum Iron with number of cigarette per day (1-15 cigarette per day) and with (16-30 cigarette per day) and weak positive correlation between serum Iron with number of cigarette per day (16-30 cigarette per day) in smokers group.
Authors and Affiliations
Ahmed Yasin Hassan1 , Salman Taha Ahmed Elmukashfi2 , Amar Mohamed Saeed2 , Abdelwahab Abdien Saeed3 , Mohammed Abd Elgadir Mahdi1
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