Evaluation of the Efficacy of Endoscopic Hemostasis with Argon Plasma Coagulation Plus Injection Sclerotherapy and Injection Sclerotherapy Alone in Acute Non-variceal Upper Gastrointestinal Bleeding
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2018, Vol 6, Issue 2
Abstract
Background: This study aims to evaluate the efficacy of endoscopic hemostasis with argon plasma coagulation (APC) plus injection sclerotherapy and injection sclerotherapy alone in acute non-variceal upper gastrointestinal (UGI) bleeding. Materials and Methods: A prospective, randomized, hospital-based study of 100 subjects divided into two groups of A and B of 50 each, comprising those who received injection sclerotherapy alone and those who received APC in addition. Results: About 94% patients in Group B had no rebleeding, compared to 76% in Group A carrying high statistical significance (Chi-square 5.563 and p 0.135). Majority of cases (6%) with rebleeding belonged to Forrest Class Ib from Group A. Mortality was more in Group A (4%) compared to Group B (2%). There were 11 (22%) patients in our study who rebled in the 1st week, 3 (6%) rebled in the 2nd week, and 1 (2%) rebled in the 3rd week. In our study, the patients who died had Rockall risk scoring system >6. Conclusion: Injection sclerotherapy supplemented with APC is superior to injection therapy alone in the endoscopic treatments of non-variceal bleeding.
Authors and Affiliations
Arshied Hussain Bhat, Masood T, Bilal Ahmad Khan, Showkat A Kadla
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