Evaluation of the Global Longitudinal Strain in FMF: In Relation with Duration of Illness
Journal Title: E Journal of Cardiovascular Medicine - Year 2020, Vol 8, Issue 4
Abstract
Objectives: The aim of this study is to investigate the effects of Familial Mediterranean Fever (FMF) on cardiac function via speckle tracking echocardiography (ECG) in pediatric FMF patients without cardiac symptoms and to compare speckle tracking ECG results with the conventional echocardiographic outcomes. Materials and Methods: A total of 50 FMF children aged between 5 and 19 years and 50 healthy children adjusted by age were evaluated for inclusion. Conventional ECG of each participant was performed to investigate mechanical myocardial function. Global longitudinal strain (GLS) measurements were performed using 2D speckle tracking ECG. Results: The mean duration of illness among FMF patients was 4.6±3.1 years. There was no statistically significant relationship between sex and duration of illness (p>0.05). GLS values measured by two-dimensional speckle tracking between the groups were significantly lower in individuals diagnosed with FMF compared to the control group (-18.0±2.0/-22.5±2.0; p<0.001). The relationship between disease duration and left ventricle-GLS values of individuals diagnosed with FMF was evaluated by spearman correlation analysis. It was observed that left ventricle-GLS values decreased statistically with increasing disease duration. Conclusion: Speckle tracking ECG can provide the chance to reveal subclinical ventricular dysfunction before cardiac dysfunctions progress in children with FMF.
Authors and Affiliations
Erhan Aygün, Fatih Mehmet Keleşoğlu, Gafur Doğdu, Ömer Kumaş, Rukiye Eker Ömeroğlu
Keywords
Related Articles
- EP ID EP691465
- DOI 10.32596/ejcm.galenos.2020.07.032
- Views 100
- Downloads 0
Being on the Edge of Amputation: Vessel-sparing Approach and Biological Bone Reconstruction in a Toddler with Extremity Rhabdomyosarcoma
Vascular reconstruction leads to surgical difficulties such as acute occlusion and critical leg ischemia in childhood rhabdomyosarcoma (RMS) pressuring on the limb’s vascular structures. Finally, amputation is inevitable...
The Relationship Between Endothelial Functions and HDL/LDL Ratios in Patients with Coronary Artery Disease
Objectives: Endothelial dysfunction plays an important role in the initial stage of atherosclerosis, the growth of atherosclerotic plaque and the development of thrombogenic events. Low-density lipoprotein (LDL) choleste...
How Much Do Routine Blood Tests Tell Us About Patent Ductus Arteriosus? Is the Red Cell Distribution Width to Platelet Count Ratio or/and Any Platelet Parameter Useful?
Objectives: In this observational study, to determine whether there is any association between red cell distribution width (RDW)/platelet count ratio (RPR) and hemodynamically significant patent ductus arteriosus (hsPDA)...
The Relation Between Thyroid Stimulating Hormone and Left Ventricular Strain Parameters in Patients with Subclinical Hypothyroidism
Objectives: In this study, it was aimed to evaluate the relationship between serum thyroid stimulating hormone (TSH) level and left ventricular strain parameters measured by the two-dimensional speckle tracking imaging a...
Evaluation of Ventricular Polarization in Noncompaction Cardiomyopathy with Electrocardiography in a Different Perspective
Objectives: Noncompaction cardiomyopathy (NCCM) is a rare genetic form of cardiomyopathy. Morphologically, it consists of a thickened two-layer myocardial structure (noncompacted-compacted layers.). In NCCM, especially i...