Evaluation of Thymic Lesions using Multidetector Row Computed Tomography and Correlation with Histopathopathological Diagnosis
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 3
Abstract
Introduction: A variety of lesions are seen involving the thymus and range from hyperplasia to innumerable tumors. Multidetector row Computed Tomography (MDCT) is a promising imaging modality which allows for substantial anatomical volumes to be covered with isotropic submillimeter spatial resolution. Aim of the study was to evaluate MDCT characteristics of thymic lesions proven by histopathology. Materials and methods: a retrospective study of 35 patients in the age group 5-78years was conducted in in the Departments of Radiodiagnosis and Pathology, Vydehi Institue of Medical Sciences and Research Centre, Bangalore between September 2011 and December 2015. Only histologically proved cases were included in the study. The size, characterization, extent, presence of calcification, invasion of the adjacent structures, lymphadenopathy and metastasis of thymic lesions were evaluated. Results: The most common thymic lesion was thymoma accounting for 34.28% of the cases followed by thymic lymphoma accounting for 22.8% of cases. Thymic hyperplasia was seen as diffuse symmetric enlargement of the gland. Thymomas were seen as homogeneous solid masses with soft tissue attenuation and well-demarcated borders. Thymic carcinomas appeared as large, multilobulated masses containing areas of low attenuation and calcification. Thymolipomas predominantly showed fat attenuation intermixed with soft tissue representing normal thymic tissue, Thymic lymphomas present as homogenous enlargement of the thymus with mediastinal or hilar lymphadenopathy. Conclusion: Multidetector row Computed Tomography plays a major role in the evaluation of thymic lesions regarding diagnosis, characterization, distribution and malignancy.
Authors and Affiliations
Madan Mohan Babu L, Niranjan Jayaram, Suresh Aswathappa, Indira Narayanaswamy
Keywords
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