Evaluation of Wound Healing Activity of Methanolic Extract of Tonna dolium (L.1758)
Journal Title: IOSR Journal of Pharmacy (IOSRPHR) - Year 2018, Vol 8, Issue 3
Abstract
Marine invertebrates offer a rich source of potential drugs with excellent biological activities. The present study was aimed at investigating the wound healing effect of methanolic extract of Tonna dolium (L.1758) using excision, incision and dead space wound model. Wound healing activity was evaluated in different concentrations prepared as simple ointment base BP using four groups of six Wistar albino rats in each model with povidone iodine (5%) as the standard drug. The wound healing was assessed by a rate of wound contraction, tensile strength and histological changes. Topical application of the methanolic extract ointments of T.dolium showed a significant and dose dependent effect on the healing process.
Authors and Affiliations
P. Subavathy1, R. D. Thilaga2 ,, A. Bavani Saraswathy3, S. Jeya Ruby
Keywords
Related Articles
- EP ID EP381142
- DOI -
- Views 110
- Downloads 0
Synthesis, characterization and antimicrobial evaluation of novel diethyl (2-phenylquinazolin-4-ylamino) (phenyl) methyl phosphate
A convenient and efficient one-pot reaction has been employed for the synthesis of new a-aminophosphonates 4a-4l via Kabachnik-Fields reaction in 89-95 % yields. In the procedure developed, equimolar quantities of...
[b] AN APPROACH FOR IMPROVEMENT OF THE WATER SOLUBILITY OF NIMESULIDE IN SOLID DISPERSION WITH PEG 4000[/b]
Pharmacological importance of Haplophyllum species grown in Iraq- A review
Haplophyllum species contained alkaloids, lignans, coumarins, flavanoids, essential oil and volatile oil. Haplophyllum species possessed many pharmacological activities included antioxidant, antimicrobial, insecticidal,...
Studies on the Effect of Diet and Drug Therapies on Serum Ferritin, a Predictor of Type 2 Diabetes Mellitus
Background and Objective: Epidemiological studies have established a link between serum ferritin concentration and type 2 diabetes. This work was carried out to ascertain the effect of therapeutic regimen on th...
[b] A comparative evaluation of in vitro growth inhibitory activities of different solvent extracts of some medicinal plants in Northern Ghana against selected human pathogens[/b]