Factors Associated With Nonalcoholic Fatty Liver Disease in Obese Adolescents
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2013, Vol 6, Issue 3
Abstract
Background and Objectives: Nonalcoholic fatty liver disease (NAFLD) is a common cause of liver disease in children and adolescents. The aim of this study is to investigate the prevalence of NAFLD in a sample of obese adolescents and to identify the clinical and biochemical characteristics in subjects with NAFLD. Design and Settings: A cross-sectional study was conducted on 366 adolescents. The data were collected from June 2011 to July 2012. Patients and Methods: The study included 202 females and 164 males. All were subjected to anthropometric, biochemical and ultrasongraphic assessment. Results: The prevalence of NAFLD in general was 57.65% (62.19% for males and 53.96% for females). Results showed statistical gender difference. There were statistical differences in BMI, WC, TG, LDL-C, HDL-C, body fat percentage (BF %), subcutaneous fat layers, visceral fat and ALT between NAFLD group and non- NAFLD group in both genders. The prevalence of obesity was significantly higher in the NAFLD group than non NAFLD group. The present study showed that 58.29% of NAFLD were obese in which 49 % of males and 67% of females. Conclusion: Abdominal obesity and dyslipidemia are risk factors for NAFLD. Prevalence of NAFLD among obese adolescents is high and prevention is extremely important.
Authors and Affiliations
Moushira Erfan Zaki| Biological Anthropology Department, Medical Research Division, National Research Centre, Cairo, Egypt, Wafaa Ezzat| Internal Medicine Department, Medical Research Division, National Research Centre, Cairo, Egypt, Yasser A Elhosary| Internal Medicine Department, Medical Research Division, National Research Centre, Cairo, Egypt, Omnia M Saleh| Internal Medicine Department, Medical Research Division, National Research Centre, Cairo, Egypt
Keywords
Related Articles
- EP ID EP8942
- DOI 10.3889/MJMS.1857-5773.2013.0311
- Views 361
- Downloads 23
Efficacy and Tolerability of Various Antimicrobial Regimens in the Treatment of Exacerbations of Chronic Bronchitis and Chronic Obstructive Pulmonary Disease in Outpatients
Objective. To compare the efficacy and tolerability of different antibiotics empirically administered for exacerbations of chronic bronchitis and chronic obstructive pulmonary disease (COPD). Methods. We performed an...
Prevalence of Superficial Fungal Infection in Primary School Children in Ahvaz, Iran
Background: Superficial fungal infections are common in schoolchildren. Superficial fungal diseases such as dermatophytosis and pityriasis versicolor, although not life-threatening, may be particularly distressing for...
Quantitative Assessment of Postural Stability and Balance Between Persons with Lower Limb Amputation and Normal Subjects by using Dynamic Posturography
Background. The amputation of lower limb constitutes a major handicap which involves a functional and professional incapacity. Balance has been reported to be a better predictor of an individual’s engagement in physi...
Leukocytic Response and Spleen Morphology of Albino Rats Exposed to Graded Levels of Lead Acetate
Aim. The study investigated the leukocytic response and spleen morphology of albino rats exposed to graded dose levels of lead acetate. Material and Methods. Four groups of 5 rats received lead acetate treatment per os...
Evaluation of Hepatoprotective Activity of Aqeous Leaf Extract of Swietenia Mahogani (Maliaceae) in Chronic Alcohol-Induced Liver Injury in Rats
Aim. This study investigated the hepatoprotective effects of aqueous leaf extract of Swietenia mahogani (Maliaceae) in chronic alcohol-induced liver injury in rats. Material and Methods. The animals were given increasi...