Factors Associated With Nonalcoholic Fatty Liver Disease in Obese Adolescents
Journal Title: Macedonian Journal of Medical Sciences (MJMS) - Year 2013, Vol 6, Issue 3
Abstract
Background and Objectives: Nonalcoholic fatty liver disease (NAFLD) is a common cause of liver disease in children and adolescents. The aim of this study is to investigate the prevalence of NAFLD in a sample of obese adolescents and to identify the clinical and biochemical characteristics in subjects with NAFLD. Design and Settings: A cross-sectional study was conducted on 366 adolescents. The data were collected from June 2011 to July 2012. Patients and Methods: The study included 202 females and 164 males. All were subjected to anthropometric, biochemical and ultrasongraphic assessment. Results: The prevalence of NAFLD in general was 57.65% (62.19% for males and 53.96% for females). Results showed statistical gender difference. There were statistical differences in BMI, WC, TG, LDL-C, HDL-C, body fat percentage (BF %), subcutaneous fat layers, visceral fat and ALT between NAFLD group and non- NAFLD group in both genders. The prevalence of obesity was significantly higher in the NAFLD group than non NAFLD group. The present study showed that 58.29% of NAFLD were obese in which 49 % of males and 67% of females. Conclusion: Abdominal obesity and dyslipidemia are risk factors for NAFLD. Prevalence of NAFLD among obese adolescents is high and prevention is extremely important.
Authors and Affiliations
Moushira Erfan Zaki| Biological Anthropology Department, Medical Research Division, National Research Centre, Cairo, Egypt, Wafaa Ezzat| Internal Medicine Department, Medical Research Division, National Research Centre, Cairo, Egypt, Yasser A Elhosary| Internal Medicine Department, Medical Research Division, National Research Centre, Cairo, Egypt, Omnia M Saleh| Internal Medicine Department, Medical Research Division, National Research Centre, Cairo, Egypt
Keywords
Related Articles
- EP ID EP8942
- DOI 10.3889/MJMS.1857-5773.2013.0311
- Views 319
- Downloads 23
Jordan B. Minov. Lung and Pleural Diseases Related to Occupational Exposures. Skopje: Pristop MK & Institute for Occupational Health of Republic of Macedonia; 2009. 247 pages; ISBN 978-9989-2713-2-8; price: MKD 600
Field of medicine: respiratory medicine, occupational medicine Audience: occupational medicine specialists, internists, allergists, otorhinolaryngologists, radiologists, epidemiologists, general practitioners Purpose:...
Neuroprotective Effects of Kolaviron, a Biflavonoid Complex of Garcinia kola, on Rats Hippocampus against MethamphetamineInduced Neurotoxicity
Aim: To investigate the protective effects of kolaviron on brain weight and behavioural performance and the histology of the hippocampus of adult Wistar rats following methamphetamine challenge. Materials and Methods:...
Extended-Spectrum Beta-Lactamase-Producing E. Coli and Klebsiella Pneumoniae in Children at University Pediatric Clinic in Skopje
Aim. The objectives of this study were to determine the prevalence and antibiotic susceptibility patterns of extended-spectrum β-lactamases (ESBL)-producing Escherichia coli and Klebsiella pneumoniae. Material and me...
Postural Stability and Balance Training Program in Hemiparetic Stroke Patients
Aim: To compare limits of stability (LOS) between stroke patients and control group and to evaluate the effects of balance training program on hemiplegic stroke patients. Setting: Balance clinic, physical medicine and...
Administrative Workload of GP’s in the Republic of Macedonia: an Urgent Call for Change
An email survey was conducted among general practitioners in the Republic of Macedonia to assess their self reported administrative workload and communication with specialists. More than 56% (55.8%) of the surveyed phy...