FLOATING DRUG DELIVERY SYSTEM: A REVIEW
Journal Title: Journal of Drug Discovery and Therapeutics - Year 2013, Vol 1, Issue 8
Abstract
Floating drug delivery systems (FDDS) was to organize the recent journalism with unique focus on the principal mechanism of floatation to achieve gastric retention. The recent developments of FDDS including the physiological and formulation variables affecting gastric retention, approaches to design single-unit and multipleunit floating systems, and their classification and formulation aspects are covered in detail. Gastric emptying of dosage forms is an extremely variable process and ability to prolong and control the emptying time is a valuable asset for dosage forms, which reside in the stomach for a longer period of time than conventional dosage forms. Gastroretentive systems can remain in the gastric region for several hours for significantly prolong residence time of drugs by which improves bioavailability, reduces drug waste, and improves solubility for drugs that are less soluble in a high pH environment.
Authors and Affiliations
Drishti Rani Ghosh *| Department of Pharmacy, University of Asia Pacific, Dhanmondi, Dhaka-1209, Rishikesh| Department of Pharmacy, University of Asia Pacific, Dhanmondi, Dhaka-1209, Md. Anwarul Haque| Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Mst Rikta Banu| Department of Pharmacy, University of Rajshahi, Rajshahi-6205, Mohammad Mahbubur Rahman| Department of Pharmacy, University of Asia Pacific, Dhanmondi, Dhaka-1209, Md. Sium-Ul Hossain Miah| Department of Pharmacy, University of Asia Pacific, Dhanmondi, Dhaka-1209, Md. Mofizur Rahman| Department of Pharmacy, Bangladesh University, Dhaka-1207
Keywords
Related Articles
- EP ID EP1440
- DOI -
- Views 483
- Downloads 31
ISOLATION OF OIL DEGRADING BACTERIA FROM OIL CONTAMINATED SOIL AND EXPRESSION OF OIL DEGRADING GENES IN NON OIL DEGRADING BACTERIA
The present study is carried out by isolation and characterization of oil degrading microbes from oil contaminated sites. In this work the Bacillus megaterium , Pseudomonas fluorescenes and S.aureus were isolated accordi...
Planning social mobilization and communication for Dengue Hemorrhagic fever Diagnosis, Treatment, Prevention and Control: A step‑by‑step guide
Dengue fever and dengue haemorrhagic fever are important arthropod-borne viral diseases. Each year, there are ~50 million dengue infections and ~500,000 individuals are hospitalized with dengue haemorrhagic fever, mainly...
MULTIFACETED USAGE OF HOLY BASIL
The unique chemistry of Tulsi is highly multifarious. Tulsi contains hundreds of beneficial compounds known as phyto-chemicals. Working together, these compounds possess strong antioxidant, antibacterial, antiviral, adap...
Formulation and Evaluation of Nanosilver Loaded Silk Fibroin Topical Gel
The skin is providing barrier to the outside protecting the body from infection, radiation, and extremes of temperature. There are various types of wounds which can damage the skin including abrasions, lacerations, ruptu...
CNS AGENTS ON HIV/AIDS: OVERVIEW
HIV/AIDS patients suffering from depression more often treated with various drugs like Methylphenidate, Dextroamphetamine to treat depression and also with psychoactive drugs to treat side effects like insomnia. Sometime...