Fluid restriction in term neonates with moderate to severe perinatal asphyxia: A randomised controlled trial
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2018, Vol 5, Issue 8
Abstract
Introduction: Management of newborns who suffer perinatal asphyxia is primarily based on supportive management, of which fluid and electrolyte management plays a very important role. We studied the role of restriction of fluids in the first 72 h in term neonates suffering from moderate to severe perinatal asphyxia. Methods: Term newborns with moderate to severe perinatal asphyxia were randomised to receive full or restricted fluids (25 newborns each) during the first 72 h of life. The primary outcome measures were mortality and neurological status at discharge. Results: Mortality among the full (FF) and restricted fluid (RF) groups was not significantly different, 4 in the FF group and 3 in the RF group with a relative risk (RR) of 1.52 [confidence interval (CI) 0.38-6.04]. The neurological status at discharge was also comparable in both the groups with RR (CI) 0.61 (0.22-1.7). Conclusion: Routine restriction of fluids in term neonates with moderate to severe perinatal asphyxia does not have any advantage.
Authors and Affiliations
Vasudha Tomar, Ruchi Rai, D. K. Singh
Keywords
Related Articles
- EP ID EP408704
- DOI 10.17511/ijpr.2018.8.06.
- Views 154
- Downloads 0
Role of cord blood bilirubin and albumin levels as predictors of subsequent hyperbilirubinemia in newborns
Introduction: Neonatal hyperbilirubinemia is one of the most common problems in term and preterm babies. Development of hyperbilirubinemia in neonates is fretful for the parents and a concern for the pediatrician too. He...
A comparative study of lipid profile in first attack versus relapse cases of idiopathic nephrotic syndrome in children
Objectives: Nephrotic dyslipoprotenemia usually revert to normal with remission but hyperlipidemia is a well known risk factor of atherosclerosis and glomerular injury in children. There are few studies comparing the spe...
Study of transcranial colour Doppler in the measurement of cerebral edema in birth asphyxia
Background: Perinatal asphyxia is an insult to fetus or newborn due to lack of oxygen /perfusion to various organs. Perinatal asphyxia occurs in 1 to 3 per 1000 live births and is related to gestational age and birth wei...
Nutritional assessment of children infected with HIV on Pre-ART & on ART
Introduction: PEM is one of the commonest manifestations of HIV in India. Malnutrition has a major impact on the outcome of HIV as it not only increases mortality but also results in an impaired response to ART. Nutriti...
Study on clinical profile and etiology of acute febrile encephalopathy in children aged between 2 months to 14 years attending to a tertiary care hospital, Eluru, Andhra Pradesh, India
Background: Acute febrile encephalopathy (AFE) is a common conditionleading to hospitalization of children in India. CNS infections are commonest cause of non-traumatic coma in children. Although AFE is one of the major...