Study of 99m-Tc DMSA (Dimercaptosuccinic acid) Scintigraphy in children with urinary tract infection
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2018, Vol 5, Issue 5
Abstract
Introduction: DMSA scan is superior to ultrasonography in detecting cortical scars, although the later identifies dilatation of the collecting systems and renal swelling. This study was conducted to know the role of 99m-Tc Dimercaptosuccinic acids (DMSA) scan in children with UTI, its role in the early detection of renal scar. Materials and Methods: A study was conducted among 125 children at Dr. B.R. Ambedkar Medical College, Bangalore from August 2015- October 2017. The study group included both inpatient and outpatient children with urinary tract infection. The patients with culture positive urinary tract infections during first and recurrent attacks were studied and followed from 3 months to 2 years. On follow- up 99m -Tc DMSA scan was conducted, if needed USG abdomen and MCU scan were conducted. Results: 44% of the children showed abnormal features both by DMSA scan and USGand 21.6% of the children had normal scan but found to have abnormality in DMSA scan. On follow- up of the children, it was noticed that in 56% of the DMSA scan was normal, in 6% of children who initially had renal scar, on follow up did not have renal scar. 24% of the children persisted to have renal scar on follow up and 12% who initially had normal DMSA scan, on follow up had scar. In that 12 children with renal scar, all the children had VUR grade 4-5. Conclusion: 99m-Tc DMSA scintigraphy is the gold standard for early identification and evaluation of acute renal inflammation and subsequent renal scarring. This study recommends both renal ultrasound scanning and 99m-Tc DMSA scintigraphy to be routinely performed in infants and children with a first febrile UTI because ultrasonography alone as low sensitivity for the detection of renal cortical abnormalities
Authors and Affiliations
Bhaskar Shenoy, Prasad Mruthyunjaya, Sunil Kumar Dodderi
Keywords
Related Articles
- EP ID EP375543
- DOI 10.17511/ijpr.2018.5.09.
- Views 148
- Downloads 0
Study of transcranial colour Doppler in the measurement of cerebral edema in birth asphyxia
Background: Perinatal asphyxia is an insult to fetus or newborn due to lack of oxygen /perfusion to various organs. Perinatal asphyxia occurs in 1 to 3 per 1000 live births and is related to gestational age and birth wei...
Coagulation Profile in Perinatal Asphyxia
Introduction: Perinatal asphyxia is a common problem with devastating consequences in neonatal practice. Bleeding due to coagulation abnormality is very common and is potentially treatable. Various mechanisms including l...
Can thyroid dysfunction in mothers influence neonatal thyroid profile?
Thyroid hormones play a critical role in normal CNS maturation. Fetus is entirely dependent on maternal thyroid hormone before the onset of endogenous thyroid hormone production. Maternal hypothyroidism alone during earl...
Langerhans cell sarcoma presenting as a mediastinal mass in a young infant: a case report
Langerhans Cell Sarcoma is an extremely rare disease. Its manifestations vary though skin, lymph-node and bone involvement are most commonly reported. It is an aggressive disease with a poor outcome. We report a six-week...
Clinical profile and outcome of cerebral malaria in pediatric cases at a tertiary Care Hospital
Background: Cerebral malaria (CM) is a potentially fatal condition encountered in all age groups and if not treated timely can cause mortality. Objective: to evaluate the clinical features of cerebral malaria in children...