Formulation and Evaluation of Beta-Cyclodextrin Complex Tablets of Ibuprofen
Journal Title: International Journal of Pharma Research and Health Sciences - Year 2016, Vol 4, Issue 1
Abstract
The objective of present study is to prepare complexes of ibuprofen with Cyclodextrin in molar ratio by co-precipitation method. The inclusion complexes was further formulated into tables by direct compression technique using superdisintegrants in order to increase the solubility of ibuprofen for improvement of dissolution rate and bioavailability. The prepared Tablets were evaluated for various pharmaceutical characteristics viz. hardness, % Friability, drug content and in-vitro release profiles
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