GROSS TOXICITIES AND HEPATOPROTECTIVE EFFECT OF ALOE VERA (L) BURM.F
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2012, Vol 3, Issue 10
Abstract
Traditional herbal drugs have a great demand in under developed countries due to their efficacy, low cost and lesser adverse effects, and they are considered to be “natural. Aloe vera at the dose of 500 mg body weight per oral was studied for the gross toxicities and hepatoprotective effect and observed the level of liver biochemical parameters in rabbits. Aloe vera showed highly significant (p<0.001) hepatoprotective effect by lowering the serum levels of serum glutamic oxaloacetate transaminase (SGOT), serum glutamic pyruvates transaminase (SGPT) and direct bilirubin. The overall experimental results suggests that Aloe vera protects the liver from oxidative stress and inhibits the excessive free radicals accumulation and possessing many hepatoprotective phytoconstituents which are biologically active such as flavonoids, alkaloids, they may be responsible for the significant hepatoprotective activity and the results justify the use of Aloe vera as a hepatoprotective agent.
Authors and Affiliations
Sultana Nuzhat , Najam Rahila
Keywords
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