Gut Microbiota and Glucose Homeostasis
Journal Title: Journal of Diabetes and Obesity - Year 2015, Vol 2, Issue 2
Abstract
The involvement of gut microbiota in type 2 diabetes has been recognized. Several Clostridium or lactobacilli species are reportedly enriched in type 2 diabetes. A study by Forslund et al, showed that gut microbes mediate the therapeutic effects of metformin through certain types of short-chain fatty acid production. Gut microbiota may therefore influence insulin sensitivity. Serum metformin levels of type 2 diabetes patients are positively correlated with Escherichia abundance, whereas they are negative correlation with Intestinibacter abundance
Authors and Affiliations
Katsunori Nonogaki
Keywords
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- EP ID EP417828
- DOI 10.15436/2376-0494.15.036
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