HbA1C and its Correlation with Lipid Profile in Acute Myocardial Infarction
Journal Title: International Journal of Contemporary Medical Research - Year 2018, Vol 5, Issue 4
Abstract
Introduction: Diabetes mellitus is present in as many as 30% of patients hospitalized with acute coronary syndromes. It has been recognized for some time that diabetics experience a greater mortality during the acute phase of myocardial infarction and a higher morbidity in the postinfarction period. The main contributory factors for these complications are uncontrolled diabetes mellitus and dyslipedemia. HBA1C level is gold standard in knowing control of diabetes mellitus and its complications. The lipid abnormalities in uncontrolled diabetes mellitus contribute to cardiovascular and peripheral vascular complication morbidity and mortality. Aims: To study the level of HbA1C and Lipid profile in patients with Acute Myocardial infarction and correlate the findings with existing literatures. Material and methods: Present prospective observational study was conducted on 100 patients admitted to the hospital with acute myocardial infarction with or without diabetes mellitus. After a detailed history and physical examination, HbA1c, lipid profile, cardiac enzymes, ECG were performed in all patients. The patients were then divided into two groups based on the HbA1c levels i.e. good glycemic control (HbA1c< 7%) and poor glycemic control (HbA1c>/= 7%). Pearson’s correlation coefficient was used to examine the association between various parameters; the linear regression graph was used. Results: Poor glycemic control was seen in 60% patients. HbA1C showed a direct correlation with triglycerides, total cholesterol, low density lipoproteins levels and indirect correlation with high density lipoproteins levels. Conclusion: HbA1C provides valuable supplementary information about the extent of circulating lipids besides its primary role in monitoring long-term glycaemic control.
Authors and Affiliations
Prithwiraj Bhattacharjee, Polok Das, Bhaskar Kanti Nath, Atanu Basumatary, Dwijen Das
Keywords
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