Hematological and Biochemical Results of Patients with Campylobacter Infection At King Fahd Hospital, Riyadh, Saudi Arabia.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 2
Abstract
Objectives: The hematological and biochemical changes due to multi-organ involvement in enteritis are common. The aim of this study was to determine the frequency and severity of the above changes in patients admitted to the hospital because of enteritis.Methodology: This was a hospital based descriptive study conducted at the infectious diseases unit and medical wards at King Fahd Hospital, Riyadh, Saudi Arabia, from 2010 to 2013. The study was designed to include demographics, hematological and biochemical changes observed in each patient. Only patients whose stool yielded Campylobacter species were included in the study. Full blood count, liver function tests, stool culture, urea, electrolytes, and coagulation profile were performed for all the patients. Results: Data on 91 patients with Campylobacter infection, corresponding to the same number of patients, were reported, including 45 (49.45%) in 2010, 28 (30.77%) in 2011, 9 (9.89%) in 2012 and 2013. Of the total number of isolates, 60 (65.93%) were from patients <20 years of age, 21 (23.08%) were from patients 20-45 years of age, 8 (8.79%) were from patients 46-71 years of age and 2 (2.19%) were from patients >71 years of age. The sensitivity of Campylobacter species to erythromycin was higher in 2010 (48.86%) compared to 2012 and 2013 (10.23%). However, two female patients were resistant to erythromycin in 2010 and one male in 2011.The most common hematological changes observed were anemia (46.2%), lymphopenia (76.9%), Neutrophilia (78%), leukocytosis (57%) & leucopenia (2.2%). Whereas, the biochemical changes included raised alkaline phosphatase (72.5%), creatinine (50.5%), potassium (44%), and blood urea (36.3%), while the serum albumin was found to be low in 78%. All patients were discharged in good health once hematological and biochemical changes returned to reference range.Conclusion: Campylobacter foodborne disease could cause significant hematological changes and hepatic dysfunction. The involvement of liver was associated with high frequency of extrahepatic complications. Despite the high incidence and serious nature of the hematological changes and liver involvement, these changes are transient and respond favorably to the appropriate antimicrobial therapy.
Authors and Affiliations
Shoeb Qureshi
Keywords
Related Articles
- EP ID EP499590
- DOI -
- Views 122
- Downloads 0
The Outcome of Children Admitted With Brochiolitis
Background and Objectives: Bronchiolitis has been one of the leading causes of infant hospitalization in the world, especially in the age group of less than one year. Susceptibility to both bronchiolitis and post-bronchi...
Cholesterol Lowering Effect Of Philippine Ashitaba (Gynura Procumbens) Crude Aqueous Leaf Extract In Hypercholesterolemic Mice
Gynura procumbens, a medicinal plant with various nutritive benefits, is being utilized as a source of total-cholesterol lowering herb in folk medicine. The Japanese variety of ashitaba has proven scientific basis in low...
Description and Outcomes of Pfiefer Wavy Repair For Tessier 7 Facial Cleft
Facial Clefts are rare types of clefts presenting with wide variety and extent of facial deformity. The most lateral type of facial cleft is called as Tessier No 7 cleft or macrostomia. This type of cleft is associated w...
Cervical Smear Findings in Perimenopausal and Postmenopausal Women: A Study of 100 Cases.
Cervical cancer is a leading cause of mortality and morbidity among women worldwide. In developing countries it is the most common gynecological cancer and one of the leading causes of cancer death among women, largely a...
A Comparative Evaluation Of Serum Lipid Profile And Uric Acid Levels In Chronic And Aggressive Periodontitis Patients Before And After Non Surgical Periodontal Therapy .
Introduction: Periodontal disease is an infectious disease which results in an increase in inflammatory cytokines, leading to mobilization of lipids from the liver and adipose tissue. Aim: Aim of the present study was to...