Vulvar Cancer – A Rare Diagnosis in Identical Twins
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 1
Abstract
Vulvar cancer is a rare neoplasm, accounting for 4% of gynecological cancers, 90% of which are squamous cell carcinomas. This tumour is more frequent in postmenopausal women, with a peak incidence in the 6th to 7th decades of life. Clinically, patients may present with vulvar ulcer, bleeding, pain, edema and leukoplakia but severe pruritus is the most common symptom. Diagnosis is based on the histological examination and the treatment is surgical. Vulvar cancer might be curable in early stages, but in locally advanced disease is associated with a poor 5 year survival rate. The authors describe two case reports of identical twins with malignant vulvar neoplasia. In literature, only one case of this malignancy is described in two twin sisters. This fact raises the hypothesis of a genetic component in the etiology of the disease.
Authors and Affiliations
Mariana Carlos Alves
Keywords
Related Articles
- EP ID EP494955
- DOI -
- Views 142
- Downloads 0
Study of Serum Magenesium in Patients with Acute Myocardial Infarction.
Acute Coronary Syndrome is a major health burden worldwide and causes more deaths and disability and incurs greater economic cost than any other illness in the world. It is also a leading cause of death in India, and its...
Dental Whitening: Case Report.
The increasing interest of aesthetic appearance in nowadays is due to its strong psychological impact on the subject itself. The multitude of solutions proposed to improve the patient’s sm...
An Evaluation of estimated GFR using serum cystatin C and creatinine in patients of essential hypertension.
Introduction: Hypertension is one of the most common worldwide disease affecting humans and is one of the leading cause of death and disability among adults all over the world. Essential hypertension accounts for 95% of...
Attitude and awareness towards organ donation in Rajasthan.
Background- The issue of organ donation is a multifactorial and complex one, involving legal, ethical, medical, organizational, and social factors. Methods- A cross-sectional study was done among 100 adult participants a...
Comparative Study of Fine Needle Aspiration Cytology and Cell Block Technique in Lymphadenopathy
Lymphadenopathy is recognized as a common sign of infectious, autoimmune, or malignant disease. Most of the times, infection is the main cause of lymphadenopathy but proper treatment can be persuaded by exact diagnosis....