Hepatitis C and Neurological Disorders A Patient’s Case Report
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2017, Vol 1, Issue 3
Abstract
Introduction: Neurological disorders associated with hepatitis C is most often related to mixed cryoglobulinemia. The aim of this study is to show the severity of neurological disorders during hepatitis c infection. Observation: Mrs. S A, 60 years old, who had been in purpuric rash for six months, associated with physical and psychic asthenia and weight loss at 16 kg in 8 months. The evolution was marked by an alteration of the neurological state of the patient with an installation of motor deficit affecting the 04 limbs, abolition of the osteo-tendinous reflexes, and a hypoesthesia of the upper and lower limbs. The electromyogram (EMG) showed a sensori-motor polyradiculo neuropathy, and the etiological diagnosis was in favor of a peripheral neuropathy secondary to a cryoglobulinemia, related to hepatitis c. In addition, the patient presented after a few days of headaches, a sharp drop in visual acuity and high blood pressure, this is complicated by two episodes of convulsive seizures. A cranial CT scan is performed in an emergency without abnormalities, with no sign in relation to thrombophlebitis after injection of contrast agent. The diagnosis retained is a central neurological disease secondary to infection with the virus c associated with peripheral neurological disease. Conclusion: Neurological disorders associated with hepatitis C are rare but poor prognosis threatening the functional and vital prognosis of patients.Hepatitis C is an infectious disease that affects the liver with predilection but also affects other organs, and is thus considered a disease of the system. Neurological damage associated with hepatitis C is most often related to mixed cryoglobulinemia, typically peripheral, sometimes central, and poor prognosis [1]. The aim of our work is to show through an observation the severity of neurological damage during hepatitis c infection.Mrs. S A, 60 years old, who had been in purpuric rash for six months, associated with physical and psychic asthenia and weight loss of 16 kg in 8 months. The evolution was marked by an alteration of the neurological state of the patient with an installation of motor deficit affecting the four limbs, abolition of the osteo-tendinous reflexes, and a hypoesthesia of the upper and lower limbs. The electromyogram (EMG) showed a sensori-motor polyradiculoneuropathy, and the etiological diagnosis was in favor of a peripheral neuropathy secondary to a cryoglobulinemia, related to hepatitis c (The viral load is 100.000 ui/ml). In addition, the patient presented after a few days of headaches, a sharp drop in visual acuity and high blood pressure, this is complicated by two episodes of convulsive seizures.
Authors and Affiliations
A Aomari, M Firwana, I Benelbarhdadi, FZ Ajana
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