Hepatitis E as a novel approaching challenge of endemic infection
Journal Title: Postępy Nauk Medycznych - Year 2014, Vol 27, Issue 11
Abstract
The paper presents basic data on the hepatitis E virus (HEV) and the disease caused by it. Traditionally, hepatitis E is regarded as a problem found in developing countries with hot climates and poor sanitation. Acute hepatitis E poses a high risk to pregnant women. In developed countries, hepatitis E has been diagnosed in people returning from trips to endemic areas. In recent years our knowledge on HEV and hepatitis E has been updated with important practical information.In this paper attention is drawn to new information on HEV infections: current classification and the genetic diversity of the virus, reports on its presence in industrialized countries as an aetiological factor of locally acquired hepatitis E and the most important routes of infection with the virus. HEV can induce various clinical types of infection, including chronic disease and non-hepatic manifestations. Populations of patients particularly prone to contracting the infection, diagnostic methods for hepatitis E and potential therapeutic options, so far available only in special cases, are presented. Interestingly, a possibility has emerged to efficiently prevent the active disease through immunization with a recombinant antigen (so far only in China).It is essential for the recognition of HEV infection to include it in the differential diagnosis of diseases with jaundice and/or unexplained hyperaminotransferasemia.The aim of this paper is to draw the attention of readers to the discussed problem in order to achieve a more detailed insight into the status of HEV infections in Poland.
Authors and Affiliations
Maciej Bura, Arleta Kowala-Piaskowska, Iwona Mozer-Lisewska
Keywords
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