Hepatoesplenomegalia by hepatosplenic gamma delta T-cell lymphoma - case report
Journal Title: Revista Uningá - Year 2021, Vol 58, Issue 1
Abstract
This report describes a case of hepatosplenic gamma delta T-cell lymphoma (LHCTGD) is a rare and rapidly progressing neoplasm, derived mainly from cytotoxic T cells. The peak incidence is in young adults, aged twenty to twenty-five years, being more prevalent in males. Clinically, patients may present abdominal pain, weakness, hepatosplenomegaly and marked thrombocytopenia, as well as systemic symptoms and absence of lymphadenopathy. In biochemical assessment is possible to observe: an increase in transaminases and alkaline phosphatase, anemia, pancytopenia and increased levels of lactate dehydrogenase. Regarding treatment, further studies are still needed, currently we have surgical intervention (splenectomy), chemotherapy regimens and hematopoietic stem-cell transplantation. This report presents the case of a 24-year-old male patient diagnosed with gamma delta T-cell hepatospelenic lymphoma and also a literature review carried out on the topic.
Authors and Affiliations
Lucas Garcez Novaes Piccinato, Isabela Pereira Almeida de Jesus, Fernando de Oliveira Dutra, Tiago Negrão Lopes, Eduarda Belasque Vriesmann, Natália Cesário de Almeida, Adorísio Bonadiman.
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