HISTOPATHOLOGICAL CHANGES OF FALLOPIAN TUBE IN UTERINE MALIGNANCIES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 14
Abstract
BACKGROUND Malignant neoplasms of uterus account for significant proportion of all female cancers, though rare in India compared to Western countries. Extrauterine involvement has a significant effect on prognosis and treatment decision. Hence, thorough sampling of uterus and adnexal structures is important for appropriate staging. Fallopian tube is not only an origin of ovarian serous carcinoma, but also an important passage for endometriosis and also has an indirect role in pathogenesis of endometrioid carcinoma, serous carcinoma and clear cell carcinoma. According to studies, fimbrial ends of fallopian tubes show more chances of lesions than the usual sampling sites like middle portion and base in classical method. The objectives of the study were to describe the histopathological changes of fallopian tube associated with uterine malignancies and to describe the findings of fallopian tube at the base, middle portion and fimbria in uterine malignancies. MATERIALS AND METHODS A descriptive study was conducted on specimens of all the cases of total abdominal hysterectomy and bilateral salpingooophorectomy diagnosed with uterine malignancies received in Department of Pathology, Govt. Medical College, Kottayam during the study period (May 2016 - May 2017). RESULTS 40 cases of uterine malignancies were studied for fallopian tube changes, of which 15 cases showed histopathological changes in fallopian tube. Of these 7 cases (46.7%) showed changes in the fimbria, 5 cases (33.3%) showed changes in the mid portion and fimbriae simultaneously, 2 cases (13.3%) showed changes in the base and one case (6.7%) showed changes in the middle portion alone. The histopathological changes were more frequent in fimbria compared to middle portion and base of fallopian tube. CONCLUSION The changes observed in fallopian tube were endometriosis, dysplasia, carcinoma, inflammation and salpingitis isthmica nodosa. The changes were more frequent in fimbria compared to middle portion and base of fallopian tube.
Authors and Affiliations
Arsha V, Lillykutty Pothen, Sankar S
Keywords
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- EP ID EP414360
- DOI 10.14260/jemds/2018/403
- Views 83
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