Histopathological spectrum of appendicular lesions and correlation with age and sex incidence: A retrospective study
Journal Title: Medpulse International Journal of Pathology - Year 2017, Vol 4, Issue 1
Abstract
Background: Among all abdominal emergency surgeries appendicitis is one of the common conditions requiring emergency surgery. A retrospective study was performed to determine various appendicular histopathological lesions, their demographics and the rates of perforated appendicitis, negative appendectomy and incidental appendectomy. Type of study: it is a cross sectional retrospective study. Materials and Methods: Resected appendices submitted to histopathology Department of Kamineni Institute of Medical Sciences, Narketpally, a teaching hospital over the period of 2 yrs from June, 2015 to July, 2017 were reviewed retrospectively. Results: Out of 1012 specimens of appendix, appendicitis accounted for 90.1% with peak age incidence in the age group of 10 to 30 yrs in both sexes. Histopathologic diagnoses included acute appendicitis (52.85%), acute suppurative (22.47%), gangrenous (17.54%), perforated (2.63%), resolving /recurrent/non specific chronic appendicitis (2.63%), acute eosinophilic appendicitis (1.53%), xanthogranulomatous appendicitis (0.21%), and carcinoid tumour (0.1%). Other important coexisting pathologies were parasitic infestation (0.2%) and Meckel’s diverticulum (0.2%). Negative appendectomy rate was 7.6% and three times more common in females with peak occurrence in the age group of 21-30 yrs. There were 10 cases of acute appendicitis in incidental appendectomies (2.27%, 23cases) with 7 times more common in females of age group of 31- 60 yrs. Conclusion: Incidence of appendicitis is high in adolescents and young adults and slightly higher in females. Negative appendectomy is also very common in females. Finally, an unusual finding such as carcinoid tumor in the clinically suspected acute appendicitis reflects the value of histological examination of every resected appendix, the presence of which would alter the further management.
Authors and Affiliations
V Vijayasree, CSPV Sunil, Sylvester Noel, T Sesagiri Rao
Keywords
Related Articles
- EP ID EP260191
- DOI -
- Views 91
- Downloads 0
A single point cytological grading system for breast carcinoma
Background: Cytological grading on fine needle aspirates of breast carcinoma is an important parameter in determining the therapy and prognosis in the era of neoadjuvant preoperative therapy. All the present grading syst...
Comparison of estrogen receptor, progesterone receptor and Ki-67 immunohistochemistry scoring using manual method and image analysis in breast carcinoma cases
Background: Breast carcinoma is the leading cause of carcinoma death in women. Estrogen receptors(ER), progesterone receptors(PR) and Ki-67 are important prognostic determinators. However immunohistochemistry (IHC) repor...
Study of platelet count, PT and aPTT in preelclampsia patients at tertiary care centre
Background: Hypertensive disorders complicate 5%-10% of all pregnancies and together they form one member of the deadly triad, along with haemorrhage and infection that contribute greatly to the maternal morbidity and mo...
Immunohistochemical study of receptor status in breast carcinoma and their correlation with histopathological grading
Background and Objectives: Breast carcinoma is the second most common cancer in many parts of India. The prognosis and management of breast carcinoma is influenced by factors like stage, grade, estrogen receptor (ER), pr...
Histopathological study on mastectomy specimens in a rural population Karaikal
Background: Breast carcinoma is the most common malignant tumor in female population. In developed countries early detection and treatment has led to the sharp decline in breast cancer mortality. But in developing countr...