Histopathological spectrum of appendicular lesions and correlation with age and sex incidence: A retrospective study
Journal Title: Medpulse International Journal of Pathology - Year 2017, Vol 4, Issue 1
Abstract
Background: Among all abdominal emergency surgeries appendicitis is one of the common conditions requiring emergency surgery. A retrospective study was performed to determine various appendicular histopathological lesions, their demographics and the rates of perforated appendicitis, negative appendectomy and incidental appendectomy. Type of study: it is a cross sectional retrospective study. Materials and Methods: Resected appendices submitted to histopathology Department of Kamineni Institute of Medical Sciences, Narketpally, a teaching hospital over the period of 2 yrs from June, 2015 to July, 2017 were reviewed retrospectively. Results: Out of 1012 specimens of appendix, appendicitis accounted for 90.1% with peak age incidence in the age group of 10 to 30 yrs in both sexes. Histopathologic diagnoses included acute appendicitis (52.85%), acute suppurative (22.47%), gangrenous (17.54%), perforated (2.63%), resolving /recurrent/non specific chronic appendicitis (2.63%), acute eosinophilic appendicitis (1.53%), xanthogranulomatous appendicitis (0.21%), and carcinoid tumour (0.1%). Other important coexisting pathologies were parasitic infestation (0.2%) and Meckel’s diverticulum (0.2%). Negative appendectomy rate was 7.6% and three times more common in females with peak occurrence in the age group of 21-30 yrs. There were 10 cases of acute appendicitis in incidental appendectomies (2.27%, 23cases) with 7 times more common in females of age group of 31- 60 yrs. Conclusion: Incidence of appendicitis is high in adolescents and young adults and slightly higher in females. Negative appendectomy is also very common in females. Finally, an unusual finding such as carcinoid tumor in the clinically suspected acute appendicitis reflects the value of histological examination of every resected appendix, the presence of which would alter the further management.
Authors and Affiliations
V Vijayasree, CSPV Sunil, Sylvester Noel, T Sesagiri Rao
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