Histopathological study in the spleen of Albino Mice treated with glucosamine sulfate drug
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 5
Abstract
The current study designed to determine the effect of Glucosamine sulfate in the spleen organ of Albino mice .the study included (24) mice divided in to 3groups (control group had distilled water orally).The other groups treated with (1500, 2500) ml/kg .respectively for (2, 3) months .the spleen have been taken from dissected animal for microscopic preparation to study. Statistical results showed that the average weight of the spleen gradually decreased as the concentration and duration of the drug increased ,The histopathologicale changes appeared in the spleen of the exposure groups during (2,3) month ,the effects were Congestion,hyperplasia,atrophy, amyloid and necrosis.
Authors and Affiliations
Lamyaa . A. Fadhil
Keywords
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