Histopathological Study of Lesions of Colon - A 5-year Study
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 2
Abstract
Introduction: Colon is part of the gastrointestinal tract that is also called the large intestine. One of the most common colon problems are inflammatory lesions, colorectal polyps, cancerous growths. Cancers of the colon and rectum altogether are the 3rd most common tumor type worldwide, and one of the leading causes of cancer-related death. Pathologic examination of biopsy, polypectomy, and resected specimens are crucial for determining local extent of disease, patient management, and prognosis assessment. This study also includes inflammatory lesions of large intestine and their etiology. Cancerous lesions are most common, and this study emphasizes on their early diagnosis and management. Aims and Objectives: The aim of this study is to study the histomorphology of various lesion of colon and to evaluate the incidence, age, and sex ratio. Materials and Methods: A 5-year study was done from January 2012 to December 2016, and a total of 102 cases were evaluated. The material for the study comprised resected specimens and biopsies of colon received in the Department of Pathology, SVS Medical College, Mahabubnagar. Results: Out of 102 cases, neoplastic lesions are 56 cases, and non-neoplastic lesions are 46 cases. Among 56 neoplastic lesions, 48 were malignant and 8 cases were benign. Most common histological variant of the malignant tumor was well-differentiated adenocarcinoma, and most common benign tumor was adenomatous polyp. The majority of the patients are between 4th-8th decade of life. Predominantly males are affected. Conclusion: Adenocarcinomas are the most common malignant lesions of colon in our study. As there is increasing incidence of malignancies early diagnosis by endoscopic biopsies in clinically suspicious patients is recommended for good management.
Authors and Affiliations
Pavani Manthini
Keywords
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