Historical aspects of endocrinology development

Abstract

The historical data on the development of medicine as a science, with an emphasis on aspects of the endocrinology, are given in this paper. The role of Ukrainian and foreign scientists and their contribution to the development of the chemistry of hormones has been clarified in a historical context. The role of schools, academies in shaping the outlook of future scientists and the promotion of best practices is shown. The article shows how the knowledge of medicine was gradually accumulated: clinical manifestations, definition of laboratory differences. The ability to provide pathogenetic treatment to the patient with endocrine disease was possible in most cases only after the industrial synthesis of hormones. The works of many scientists were awarded the Nobel Prize in medicine and physiology. The definition of “hormone”, classification, place of biosynthesis, particularly of the secretion, the industrial synthesis of some of them and the scope of use are presented. Special attention is paid to the description of new methods of synthesis of thyroxine, flutapharm and other substances.

Authors and Affiliations

M. D. Tronko, Ya. H. Balon, O. Ya. Samson

Keywords

Related Articles

PCNA expression as a marker of proliferation in benign and highly differentiated malignant tumors of the human thyroid gland (literature review and clinical case)

Determining of the proliferative potential of tumor cells is an important task for the diagnosis of thyroid cancer. Therefore, a search for markers characterizing the state of proliferative processes is necessary. Prolif...

Hormonal and Biochemical Characteristic of Patients with Ischemic Heart Disease and Adult Growth Hormone Deficiency

In this article the authors analyzed the results of examination of 21 adult patients with ischemic heart disease against adult growth hormone deficiency. The decreasing of mean levels of growth hormone, LH in men and FSH...

Pharmacoeconomic Analysis of Prolonged Insulin Analogues Usage in Type 2 Diabetes Mellitus under the Conditions of Ukrainian Pharmaceutical Market

The paper is dedicated to the insulin therapy of diabetes mellitus. There was performed a comparative clinical and economic estimation of insulin analogues (Lantus® and Levemir®). Due to it insulin glargine was found to...

Evaluating the Possibility of Diabetes Mellitus in Different Levels of Cardiovascular Risk in Men

This paper evaluated the possibility of diabetes mellitus (DM) type 2 in men with different risks of cardiovascular disease, as well as clarified the relationship between high risk of DM type 2 and the main factors of ca...

Blood glucose level and insulin resistance in patients with type 2 diabetic mellitus, diabetic retinopathy and obesity

Background. Diabetic retinopathy is the main cause of visual disorders in the world. The purpose of our work was to study the level of glycaemia and insulin resistance in patients with type 2 diabetes mellitus (DM), diab...

Download PDF file
  • EP ID EP212792
  • DOI 10.22141/2224-0721.13.3.2017.104472
  • Views 84
  • Downloads 0

How To Cite

M. D. Tronko, Ya. H. Balon, O. Ya. Samson (2017). Historical aspects of endocrinology development. Міжнародний ендокринологічний журнал, 13(3), 219-225. https://europub.co.uk/articles/-A-212792