HIV infection among voluntary blood donors in Shijiazhuang, 2011-2021
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 2
Abstract
Objective To study the characteristics of HIV infection among voluntary blood donors in Shijiazhuang from 2011 to 2021, so as to provide reference for decision making in the control of HIV for blood centers. Methods The confirmatory results of HIV reactive samples in initial screening among voluntary blood donors from 2011 to 2021 in our center were statistical analyzed. Results A total of 2 008 299 samples from 1 667 315 blood donors were detected, among which 3 217 samples were HIV reactive and 234 were confirmed positive, with the positive rate at 11.65/100 000 and the prevalence of 14.03/100 000. The prevalence in men was higher than that in women (16.52/100 000 vs 1.39/100 000), in first-time blood donors higher than that in repeated donors (17.27/100 000 vs 8.12/100 000), in whole blood donors higher than that in plateletpheresis donors (12.01/100 000 vs 8.41/100 000), and the differences were statistically significant (P<0.05). The male homosexual transmission was the main routes of transmission, accounting for 62.39% (146/234). And 72% of double-reagent reactive samples were confirmed positive. Four samples were screened in the serological window period and 6 samples were from HIV positive confirmed donors. Conclusion The HIV prevalence among voluntary blood donors in Shijiazhuang was low. A certain percentage of repeated blood donors got newly infected. NAT could shorten the detection window period of HIV. Since some confirmed positive samples had not been detected out by NAT, publicity and education should be strengthened to reduce the probability of infected or high-risk groups to participate in blood donation.
Authors and Affiliations
Yazi ZHAO, Xianyuan WANG, Yanbin WANG, Huixian ZHANG, Wei HAN
Detection results of blood donors with HBsAg reactivity to single reagent: a retrospective analysis
Objective To retrospectively analyze the detection results of blood donors with HBsAg reactivity to single reagent detected by enzyme-linked immunosorbent assay (ELISA) in our center, so as to provide basis for further c...
Investigation of rare hemoglobin-coding gene defects among Chinese population
Objective To summarize the types of rare hemoglobin-coding gene defects and their phenotypes in Chinese population, aimed at providing reference for genetic counseling of couples in childbearing age from areas with high...
Analysis of confidential unit exclusion status of voluntary blood donors in Hefei
Objective To explore the status of confidential unit exclusion(CUE) status among voluntary blood donors in Hefei, so as to provide scientific basis for blood safety. Methods From 2012 to 2021, 57 out of the 1 158 272 vol...
Construction of a consistency evaluation system for a nucleic acid testing kit: a preliminary study
Objective To evaluate the performance of a blood nucleic acid testing kit, construct a consistency assessment system, and analyze the influencing factors of the test results. Methods A total of 18 644 samples of voluntar...
Effects of overall planning on staff burnout and group blood donation errors
Objective To analyze the causes of staff burnout and various errors during group blood donation in blood centers, and to explore the significance of overall planning to improve above problems. Methods Various errors occu...