HIV infection and hepatic enzymes abnormalities: A hospital based study among the HIV infected women of India
Journal Title: Indian Journal of Obstetrics and Gynecology Research - Year 2018, Vol 5, Issue 2
Abstract
Introduction Globally HIV infection has become a serious public health problems as it is responsible for millions of deaths every year and the women are the most vulnerable to HIV infection in the developing and underdeveloped countries The liver enzymes alteration is a useful indicator of the HIV severity of the body nbspThis study was designed to find the effect of CD4 count and nutritional status on liver enzymes among HIV and HIV women living in West BengalMaterials and Methods This hospital based cross sectional study was performed among 97 women at Midnapore Medical College and Hospital Midnapore India Blood samples were collected from the participants to determine CD4 count Serum glutamate oxaloacetate transaminase SGOT serum glutamic pyruvate transaminase SGPT and alkaline phosphates ALP Anthropometric measurements were taken using the standard techniquesResults HIV women 2042plusmn1763 kgm2 were significantly heavier t4172 Plt0001 than the HIV one 1852plusmn263 kgm2 Similarly the HIV women 99592plusmn10024 cellsmicrol had higher level of CD4 than the HIV women 37422plusmn18566 cellsmicrol at significant level t20459 Plt0001 The Odd ratio indicated that the elevated SGPT SGOT and ALP were 1250 1520 and 14400 times higher among the HIVnbspthan HIVminusnbspwomenDiscussion HIVinfected women are at a greater risk of abnormal liver function and this abnormality increases with the severity of the disease conditionKeywords CD4 count Antiretroviral therapy Human immunodeficiency virus infection Liver function
Authors and Affiliations
Soumitra Barick, Sandip Chattopadhyay, Nirmalya Kumar Sinha, Bulbul Purkait
Keywords
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- EP ID EP475290
- DOI 10.18231/2394-2754.2018.0043
- Views 56
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