Human granulocytic anaplasmosis (HGA) – diagnostic and therapeutic recommendations. Analysis of a clinical case
Journal Title: Postępy Nauk Medycznych - Year 2014, Vol 27, Issue 11
Abstract
Human granulocytic anaplasmosis (HGA), tick-borne diseases, gives a variety of clinical symptoms what makes diagnosis difficult. Moreover, according to recent reports in the literature affecting more and more patients. Increasing incidence is associated with higher recreational activity wooded areas. Incorrect diagnosis and hence incorrect treatment of the infection, may lead to death of the patient. Taking into account the differential diagnosis of tick-borne diseases should be aware of HGA.We present a case report of patient who had been bitten by a tick and after a few days presented fever, stomachache, arthralgia and muscle aches. Many other diseases entities responsible for these symptoms were taken into account in the differential diagnosis.Therapeutic decision was based upon history, physical examination and results of additional laboratory tests. Immediate clinical improvement occurred after administration of doxycycline. Based on current guidelines of European Society of Clinical Microbiology and Infectious Diseases (ESCMID) certain diagnosis was established few months later after hospitalization, by serological test due to demonstrate the presence of IgM antibodies and a decrease IgG antibodies to Anaplasma phagocytophilum. Article contains current diagnostics and therapeutic recommendations for anaplasmosis.
Authors and Affiliations
Agnieszka Pokora-Pachowicz, Elżbieta Bryłowska, Justyna Stempkowska, Krzysztof Tomasiewicz
Keywords
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