Hypercalcemic Crisis, Can be Iatrogenic
Journal Title: Pediatric Education and Research - Year 2019, Vol 7, Issue 2
Abstract
The recommended upper limits for long term vitamin D intake are 1000 IU for children <1 year old and 2000 IU for older children and adults. Vitamin D intoxication can occur with long term high intake or with a substantial acute ingestion. Excess 25 (OH) D causes bone resorption and intestinal absorption of calcium leading to hypercalcemia. Hypercalcemia is defined as a serum calcium concentration that is greater than two standard deviations above the normal mean. Hypercalcemia is generally considered to be mild, moderate, and severe for total serum calcium concentrations <12 mg/dL (3.00 mmol/L), between 12 and 14 mg/dL (3.00 to 3.50 mmol/L), and >14 mg/dL (3.50 mmol/L), respectively. Children with vitamin D intoxication present with symptoms of hypercalcemia, such as poor appetite, weight loss, abdominal pain, vomiting, constipation, polyuria, and polydipsia, and in severe cases, life-threatening dehydration. We report a case of hypercalcemic crisis presenting in emergency department.
Authors and Affiliations
Sunil Kumar Rao
Keywords
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- EP ID EP649436
- DOI 10.21088/per.2321.1644.7219.6
- Views 59
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