Hypolipidemic activity of Trichopus zeylanicus leaf extract against alloxan induced diabetes mellitus in male albino rats.
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 1
Abstract
Trichopus zeylanicus is a plant with adaptogenic properties. This experiment with three groups of rats was designed to evaluate the beneficial properties of T. zeylanicus consumption on LPO, AO, blood glucose regulation and lipid profile in albino rats in alloxan induced stage. For the study, the male albino rats were divided into three groups normal, alloxan treated and alloxan along with the plant treated group. The Intraperitonial injection of alloxan with two days caused diabetes mellitus and the third group had plant treatment up to 5 days. Effects of T. zeylanicus consumption on LPO, antioxidant, GSH, glucose and lipid profile were also evaluated. The plant treatment had remarkable effects on LPO, GSH and glucose level in the male albino rats. An improvement in lipid profile was observed with lower plasma LDL and total- cholesterol levels as well as higher HDL cholesterol after 5 days of T. zeylanicus leaf extract treatment. Thus the leaf extract of T. zeylanicus was found to have hypolipidemic activity.
Authors and Affiliations
S. Rajprakash
Keywords
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