IMPACT OF ENDOTOXIN ON PHYSIOLOGICAL RESPONSES OF RAT EXPOSED TO TEXTILE ENVIRONMENT
Journal Title: International Journal of Pharmaceutical Applications - Year 2011, Vol 2, Issue 3
Abstract
Occupational health hazards among people exposed to various types of organic and inorganic dusts are known for centuries. Industrialization has led to operating of machines in enclosed spaces and handling of synthetic and natural fibers on such machines creates a new microenvironment. Cotton textile industry is the single largest industry employing lacs of workers, but the powerloom sector of this industry is operating with adverse working conditions without any research or innovation. The animal model rat has been developed by our laboratory to study effects of occupational stresses and hazards on exposure to textile environment.Serum protein profile showed increase α and β- globulins and decreased total proteins and albumin level. Agglutination assay shows C-Reactive protein. The present findings suggest extrapulmonary activity of inhaled particles in the textile environment besides the pulmonary effects.
Authors and Affiliations
Monica R Sanandam
Keywords
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